Hepatitis C E2 Antigen antibody

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Goat anti Hepatitis C E2 Antigen

Product Type: Polyclonal Antibody
Isotype: Polyclonal IgG

Product Code	Applications	Datasheet	MSDS	Pack Size	List Price	Quantity
OBT0993	E IF WB			1 ml

Goat anti Hepatitis C E2 antigen antibody recognizes the Hepatitis C virus envelope glycoprotein E2, a 333 amino acid single pass type 1 transmembrane protein also known as NSA, gp68 or gp70. The E2 protein forms a heterodimer with the Envelope glycoprotein E1 and is involved in viral entry into cells. The E2 protein acts as a ligand for CD209 and CLEC4M found on dendritic cells and liver sinusoidal endothelial cells respectively. CLEC4M is also found lymph nide sinusoidal macrophage like cells (UniProt: P26664).

Product Details

Target Species: Viral
Product Form: Ig Fraction - liquid
Buffer Solution: Phosphate buffered saline
Preservative Stabilisers: 0.09% Sodium Azide (NaN₃)
Immunogen: Recombinant E2 (genotype 1a).
Approx. Protein Concentrations: 1.0 mg/ml

Storage Information

Storage: Store at +4^oC or at -20^oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

More Information

UniProt: P26664 Related reagents
GO Terms: GO:0004197 cysteine-type endopeptidase activity; GO:0003723 RNA binding; GO:0030529 ribonucleoprotein complex; GO:0004252 serine-type endopeptidase activity; GO:0003968 RNA-directed RNA polymerase activity; GO:0006915 apoptosis; GO:0016021 integral to membrane; GO:0004386 helicase activity; GO:0005198 structural molecule activity; GO:0005524 ATP binding; GO:0005789 endoplasmic reticulum membrane; GO:0006410 transcription, RNA-dependent; GO:0006508 proteolysis; GO:0019079 viral genome replication; GO:0008270 zinc ion binding; GO:0017124 SH3 domain binding; GO:0019028 viral capsid; GO:0019031 viral envelope; GO:0019087 transformation of host cell by virus; GO:0020002 host cell plasma membrane; GO:0030683 evasion by virus of host immune response; GO:0042025 host cell nucleus; GO:0044167 host cell endoplasmic reticulum membrane; GO:0044186 host cell lipid particle; GO:0044191 host cell mitochondrial membrane; GO:0044220 host cell perinuclear region of cytoplasm; GO:0045449 regulation of transcription; GO:0055036 virion membrane
Regulatory: For research purposes only

Applications of Hepatitis C E2 Antigen antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
ELISA
Immunofluorescence
Western Blotting

Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

Secondary Antibodies Available

Description	Product Code	Pack Size	Applications	List Price	Quantity
Rabbit anti Goat IgG (Fc):FITC	STAR122F	1 mg	F
Rabbit anti Goat IgG (Fc):HRP	STAR122P	1 mg	C E WB