Histone H4 Ac5 antibody
Rabbit anti Histone H4 (Ac5)
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- Histone H4 Ac5
Rabbit anti Histone H2 (Ac5) antibody recognizes Histone H4 when acetylated at lysine 5. |
- Target Species
- Synthetic Peptide
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mammals Expected from Sequence Drosophila Amphibia Expected from Sequence Yeast Plants Expected from Sequence - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Serum - liquid
- Antiserum Preparation
- Antisera to acetylated histone H4 were raised by repeated immunisation of rabbits with highly purified antigen.
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3)
- Immunogen
- Ovalbumin-conjugated peptide: NSGRGAcKGGKGLCc.
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Chromatin Immunoprecipitation | |||
ELISA | 1/1000 | ||
Immunofluorescence | 1/400 | ||
Immunoprecipitation | |||
Western Blotting | 1/600 |
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg | Log in | |||
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Description | Goat anti Rabbit IgG (Fc):Biotin | ||||||
Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg | Log in | |||
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Description | Goat anti Rabbit IgG (Fc):FITC | ||||||
Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg | Log in | |||
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Description | Goat anti Rabbit IgG (Fc):HRP | ||||||
Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg | Log in | |||
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Description | Goat anti Rabbit IgG (H/L):HRP | ||||||
Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml | Log in | |||
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Description | Sheep anti Rabbit IgG:RPE |
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
TidyBlot Western Blot Detection Reagent:HRP | STAR209P | WB * | 0.5 ml | Log in | |||
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Description | TidyBlot Western Blot Detection Reagent:HRP |
Source Reference
-
Turner, B.M. et al. (1989) Histone H4 acetylation in human cells. Frequency of acetylation at different sites defined by immunolabeling with site-specific antibodies.
FEBS Lett. 253 (1-2): 141-5.
References for Histone H4 Ac5 antibody
-
Turner, B.M. et al. (1992) Histone H4 isoforms acetylated at specific lysine residues define individual chromosomes and chromatin domains in Drosophila polytene nuclei.
Cell. 69 (2): 375-84. -
Belyaev, N. et al. (1996) Differential underacetylation of histones H2A, H3 and H4 on the inactive X chromosome in human female cells.
Hum Genet. 97 (5): 573-8. -
Ito, K. et al. (2000) Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta-induced histone H4 acetylation on lysines 8 and 12.
Mol Cell Biol. 20: 6891-903. -
Lacoste, N. et al. (2002) Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase.
J Biol Chem. 277: 30421-4. -
Nie, M. et al. (2003) Transcriptional regulation of cyclooxygenase 2 by bradykinin and interleukin-1beta in human airway smooth muscle cells: involvement of different promoter elements, transcription factors, and histone h4 acetylation.
Mol Cell Biol. 23: 9233-44. -
Tanny, J.C. et al. (2004) Budding yeast silencing complexes and regulation of Sir2 activity by protein-protein interactions.
Mol Cell Biol. 24: 6931-46. -
Nie, M. et al. (2005) beta2-Adrenoceptor agonists, like glucocorticoids, repress eotaxin gene transcription by selective inhibition of histone H4 acetylation.
J Immunol. 175: 478-86. -
Spada, F. et al. (2005) Histone H4 post-translational modifications in chordate mitotic and endoreduplicative cell cycles.
J Cell Biochem. 95: 885-901.
View The Latest Product References
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McManus, K.J. et al. (2006) The transcriptional regulator CBP has defined spatial associations within interphase nuclei.
PLoS Comput Biol. 2: e139. -
Auger, A. et al. (2008) Eaf1 is the platform for NuA4 molecular assembly that evolutionarily links chromatin acetylation to ATP-dependent exchange of histone H2A variants.
Mol Cell Biol. 28: 2257-70. -
Tsaprouni, L.G. et al. (2011) Differential patterns of histone acetylation in inflammatory bowel diseases.
J Inflamm (Lond). 8 (1): 1. -
Krogan, N.T. et al. (2012) APETALA2 negatively regulates multiple floral organ identity genes in Arabidopsis by recruiting the co-repressor TOPLESS and the histone deacetylase HDA19.
Development. 139: 4180-90. -
Havasi, A. et al. (2013) Histone Acetyl Transferase (HAT) HBO1 and JADE1 in Epithelial Cell Regeneration.
Am J Pathol. 182: 152-62.
- RRID
- AB_567394
- UniProt
- P62805
- Entrez Gene
- HIST2H4B
- GO Terms
- GO:0005515 protein binding
- GO:0000723 telomere maintenance
- GO:0000786 nucleosome
- GO:0003677 DNA binding
- GO:0005654 nucleoplasm
- GO:0048015 phosphatidylinositol-mediated signaling
- GO:0034080 CenH3-containing nucleosome assembly at centromere
- GO:0045653 negative regulation of megakaryocyte differentiation
AHP962
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