Rabbit anti SP-1 Glycoprotein antibody
recogniszes SP-1 also known as Schwangerschaft's protein 1 or pregnancy β1glycoprotein, a glycoprotein marker synthesized in the syncytrotrophoblast of the placenta and secreted into maternal circulation as gestation progresses (Griffiths and Godard 1981
). SP-1 glycoprotein has been extensively investigated as an indicator of pregnancy affected by trisomy, particularly as an idicator of down's syndrome affected pregnancy where it appears that maternal levels of SP-1 glycoprotein are significantly elevated compared to uneventful pregnancy (Bartels et al. 1988
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein G
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Approx. Protein Concentrations
- IgG concentration 5.0 mg/ml
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted.
Avoid repeated freezing and thawing as this may denature the antibody.
Should this product contain a precipitate we recommend microcentrifugation before use.
- 18 months from date of despatch.
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of SP-1 Glycoprotein antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
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Secondary Antibodies Available
Useful Reagents Available