Rabbit anti STAT2 antibody recognizes signal transducer and activator of transcription 2 (STAT2), a member of the STAT protein family, which plays an important role in cell growth, survival differentiation and transformation, transducing signals from cytokine receptors to the nucleus. STAT2 is tyrosine phosphorylated by members of the Janus kinase family in response to cytokines and growth factor stimulation. Phosphorylation results in STAT activation and the formation of STAT2 homo- or STAT2/STAT1 heterodimers. STAT dimers translocate from the cytoplasm to the nucleus where they act as transcription factors. Deregulated JAK/STAT signaling has been implicated in a variety of cancers; STATs can regulate the tumor microenvironment and trigger a shift from cancer inhibition to promotion.
- Target Species
- Species Cross-Reactivity
Target Species Cross Reactivity Human Mouse
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 30% Glycerol
0.5% Bovine Serum Albumin
- Synthetic peptide surrounding amino acid 615 of rat STAT2
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- Shelf Life
- 12 months from date of despatch
Applications of STAT2 antibody
|Application Name||Verified||Min Dilution||Max Dilution|
|Western Blotting||0.5||4.0 ug/ml|
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti STAT2 antibody recognizes a band of approximately 113 kDa in Jurkat cell lysate and 3T3 cell lysate
Copyright © 2018 Bio-Rad Antibodies (formerly AbD Serotec)
Secondary Antibodies Available
|Description||Product Code||Pack Size||Applications||List Price||Quantity|
|Sheep anti Rabbit IgG:Biotin||2AB02B||1 ml||C E P WB|
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|Goat anti Rabbit IgG (Fc):HRP||STAR121P||1 mg||E WB|
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|Sheep anti Rabbit IgG:DyLight®488||STAR36D488GA||0.1 mg||F IF WB|
|Sheep anti Rabbit IgG:DyLight®549||STAR36D549GA||0.1 mg||F IF|
|Sheep anti Rabbit IgG:DyLight®649||STAR36D649GA||0.1 mg||F IF|
|Sheep anti Rabbit IgG:DyLight®680||STAR36D680GA||0.1 mg||F IF WB|
|Sheep anti Rabbit IgG:Dylight®800||STAR36D800GA||0.1 mg||F IF WB|