Prolactin antibody

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Rabbit anti Rat Prolactin

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Product Code Applications Pack Size List Price Quantity
7770-5004G
Datasheet
C E
MSDS
0.25 ml loader

Rabbit anti Rat prolactin antibody recognizes prolactin, a secreted protein with hormonal activity, which functions by binding to the prolactin receptor and positively regulating epithelial cell proliferation. Prolactin acts primarily on the mammary gland by promoting lactation, and has been shown to promote prostate epithelial cell proliferation(Ahonen et al. 1999). Prolactin may also facilitate decidual growth and placentation. Prolactin belongs to the somatotropin/prolactin family.

Product Details

Target Species
Rat
Product Form
Purified IgG - liquid
Antiserum Preparation
Antisera to prolactin were raised by repeated immunisations of rabbit with highly purified antigen. IgG fraction prepared by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09%Sodium Azide (NaN3)
Immunogen
Purified rat prolactin from pituitary glands.
Approx. Protein Concentrations
IgG concentration 5.0mg/ml

Storage Information

Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Guarantee
18 months from date of despatch.

More Information

UniProt
P01237 Related reagents
Entrez Gene
Prl Related reagents
GO Terms
GO:0005576 extracellular region
GO:0005148 prolactin receptor binding
GO:0005179 hormone activity
GO:0030141 stored secretory granule
GO:0007567 parturition
GO:0007584 response to nutrient
GO:0007595 lactation
GO:0007623 circadian rhythm
GO:0042493 response to drug
GO:0014070 response to organic cyclic compound
GO:0030278 regulation of ossification
GO:0032355 response to estradiol stimulus
GO:0032496 response to lipopolysaccharide
GO:0032870 cellular response to hormone stimulus
GO:0033555 multicellular organismal response to stress
GO:0042698 ovulation cycle
GO:0045471 response to ethanol
GO:0050679 positive regulation of epithelial cell proliferation
Regulatory
For research purposes only

Applications of Prolactin antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1/50 1/200
Immunohistology - Frozen
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Sheep anti Rabbit IgG:Biotin 2AB02B C E P WB 1 ml loader
Goat anti Rabbit IgG (Fc):Biotin STAR121B E WB 1 mg loader
Goat anti Rabbit IgG (Fc):FITC STAR121F F 1 mg loader
Goat anti Rabbit IgG (Fc):HRP STAR121P E WB 1 mg loader
Goat anti Rabbit IgG (H/L):HRP STAR124P C E WB 1 mg loader
Sheep anti Rabbit IgG:FITC STAR34B C F 1 mg loader
Sheep anti Rabbit IgG:RPE STAR35A F 1 ml loader
Sheep anti Rabbit IgG:DyLight®488 STAR36D488GA F IF WB 0.1 mg loader
Sheep anti Rabbit IgG:DyLight®680 STAR36D680GA F IF WB 0.1 mg loader
Sheep anti Rabbit IgG:Dylight®800 STAR36D800GA F IF WB 0.1 mg loader

Product Specific References

References for Prolactin antibody

  1. Alam, S.M. et al. (2006) The rat prolactin gene family locus: species-specific gene family expansion.
    Mamm Genome. 17 (8): 858-77.
  2. Gourdji, D. & Laverrière, J.N. (1994) The rat prolactin gene: a target for tissue-specific and hormone-dependent transcription factors.
    Mol Cell Endocrinol. 100 (1-2): 133-42.
  3. Farris, G.M. et al. (2007) Recombinant rat and mouse growth hormones: risk assessment of carcinogenic potential in 2-year bioassays in rats and mice.
    Toxicol Sci. 97: 548-61.