Rabbit anti Rat prolactin antibody
recognizes prolactin, a secreted protein with hormonal activity, which functions by binding to the prolactin receptor and positively regulating epithelial cell proliferation. Prolactin acts primarily on the mammary gland by promoting lactation, and has been shown to promote prostate epithelial cell proliferation(Ahonen et al. 1999
). Prolactin may also facilitate decidual growth and placentation. Prolactin belongs to the somatotropin/prolactin family.
- Target Species
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antisera to prolactin were raised by repeated immunisations of rabbit with highly purified antigen. IgG fraction prepared by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- Purified rat prolactin from pituitary glands.
- Approx. Protein Concentrations
- IgG concentration 5.0mg/ml
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 18 months from date of despatch.
- Entrez Gene
- GO Terms
prolactin receptor binding
stored secretory granule
response to nutrient
response to drug
response to organic cyclic compound
regulation of ossification
response to estradiol stimulus
response to lipopolysaccharide
cellular response to hormone stimulus
multicellular organismal response to stress
response to ethanol
positive regulation of epithelial cell proliferation
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of Prolactin antibody
|Immunohistology - Frozen
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Copyright © 2019 Bio-Rad Antibodies (formerly AbD Serotec)
Secondary Antibodies Available
Product Specific References
References for Prolactin antibody
Alam, S.M. et al. (2006) The rat prolactin gene family locus: species-specific gene family expansion.
Mamm Genome. 17 (8): 858-77.
Gourdji, D. & Laverrière, J.N. (1994) The rat prolactin gene: a target for tissue-specific and hormone-dependent transcription factors.
Mol Cell Endocrinol. 100 (1-2): 133-42.
Farris, G.M. et al. (2007) Recombinant rat and mouse growth hormones: risk assessment of carcinogenic potential in 2-year bioassays in rats and mice.
Toxicol Sci. 97: 548-61.