Leptin antibody

Filter by Application:
IF ResetGoat anti Rat Leptin
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- Leptin
Goat anti Rat Leptin antibody specifically recognizes rat leptin, a major adipose-derived hormone and member of the leptin family, which plays a key role in appetite control and the regulation of energy expenditure. Leptin is a recognized marker of obesity, which signals through binding to the obesity receptor (OB-R) in the hypothalamus. In humans there is a correlation between circulating levels of leptin and body fat mass, and defects in leptin production result in severe obesity. Regulators of leptin expression include insulin, cortisol, cAMP and thiazolidinediones. |
- Target Species
- Rat
- Product Form
- Purified IgG - lyophilized
- Reconstitution
- Reconstitute with 0.1ml distilled water
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution. For long term storage the addition of 0.09% sodium azide is recommended. - Antiserum Preparation
- Antiserum to rat Leptin were raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- None present
- Carrier Free
- Yes
- Immunogen
- Recombinant rat leptin.
- Approx. Protein Concentrations
- IgG concentration 1.0mg/ml after reconstitution
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
After reconstitution store at -20°C.
This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA | ![]() |
0.5 | 2.0ug/ml |
Western Blotting | ![]() |
0.1 | 0.2ug/ml |
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Rabbit anti Goat IgG (Fc):FITC | STAR122F | F | 1 mg |
![]() |
Log in | ||
List Price | Your Price | ||||||
![]() |
Log in | ||||||
Description | Rabbit anti Goat IgG (Fc):FITC | ||||||
Rabbit anti Goat IgG (Fc):HRP | STAR122P | C E WB | 1 mg |
![]() |
Log in | ||
List Price | Your Price | ||||||
![]() |
Log in | ||||||
Description | Rabbit anti Goat IgG (Fc):HRP |
References for Leptin antibody
-
Hue-beauvais, C. et al. (2019) Impact of exposure to diesel exhaust during pregnancy on mammary gland development and milk composition in the rabbit.
PLoS One. 14 (2): e0212132.
- RRID
- AB_2136211
- UniProt
- P50596
- Entrez Gene
- Lep
- GO Terms
- GO:0001542 ovulation from ovarian follicle
- GO:0005125 cytokine activity
- GO:0005179 hormone activity
- GO:0005615 extracellular space
- GO:0006112 energy reserve metabolic process
- GO:0007259 JAK-STAT cascade
- GO:0008343 adult feeding behavior
- GO:0009062 fatty acid catabolic process
- GO:0009892 negative regulation of metabolic process
- View More GO Terms
- GO:0019933 cAMP-mediated signaling
- GO:0032099 negative regulation of appetite
- GO:0033210 leptin-mediated signaling pathway
- GO:0043410 positive regulation of MAPKKK cascade
- GO:0051428 peptide hormone receptor binding
AAR40


If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
View all Anti-Rat ProductsAlways be the first to know.
When we launch new products and resources to help you achieve more in the lab.
Yes, sign me up