STAT5A antibody

Filter by Application:
WB ResetRabbit anti STAT5A
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- STAT5A
Rabbit anti STAT5A antibody recognizes signal transducer and activator of transcription 5A (STAT5A), a member of the STAT protein family. STAT5A plays an important role in cell growth, survival, differentiation and transformation by transducing signals from cytokine receptors to the nucleus. STAT5A is tyrosine phosphorylated by members of the Janus kinase (JAK) family in response to cytokines and growth factor stimulation. Phosphorylation results in STAT activation and the formation of STAT5 homo- and STAT5/STAT3 heterodimers. STAT dimers translocate from the cytoplasm to the nucleus where they act as transcription factors. Deregulated JAK/STAT signaling has been implicated in a variety of cancers, and STATs can regulate the tumor microenvironment to trigger a shift from cancer inhibition to promotion. |
- Target Species
- Mouse
- Species Cross-Reactivity
-
Target Species Cross Reactivity Human Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography
- Antiserum Preparation
- Antiserum to STAT5A was raised by repeated immunisation of rabbits with highly purified antigen
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.1% Sodium Azide (NaN3)
0.2% Gelatin - Immunogen
- Peptide mapping to the carboxy terminus of mouse STAT5A
- Approx. Protein Concentrations
- IgG concentration 0.2 mg/mll
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Western Blotting | ![]() |
1/200 |
- Western Blotting
- Rabbit anti STAT5A recognizes a band of approximately 91 kDa when run under reducing conditions
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg |
![]() |
Log in | ||
List Price | Your Price | ||||||
![]() |
Log in | ||||||
Description | Goat anti Rabbit IgG (Fc):Biotin | ||||||
Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg |
![]() |
Log in | ||
List Price | Your Price | ||||||
![]() |
Log in | ||||||
Description | Goat anti Rabbit IgG (Fc):FITC | ||||||
Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg |
![]() |
Log in | ||
List Price | Your Price | ||||||
![]() |
Log in | ||||||
Description | Goat anti Rabbit IgG (Fc):HRP | ||||||
Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg |
![]() |
Log in | ||
List Price | Your Price | ||||||
![]() |
Log in | ||||||
Description | Goat anti Rabbit IgG (H/L):HRP | ||||||
Sheep anti Rabbit IgG:FITC | STAR34B | C F | 1 mg |
![]() |
Log in | ||
List Price | Your Price | ||||||
![]() |
Log in | ||||||
Description | Sheep anti Rabbit IgG:FITC | ||||||
Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
![]() |
Log in | ||
List Price | Your Price | ||||||
![]() |
Log in | ||||||
Description | Sheep anti Rabbit IgG:RPE |
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
TidyBlot Western Blot Detection Reagent:HRP | STAR209P | WB* | 0.5 ml | Log in | |||
List Price | Your Price | ||||||
Log in | |||||||
Description | TidyBlot Western Blot Detection Reagent:HRP |
- UniProt
- P42230
- Entrez Gene
- Stat5a
- GO Terms
- GO:0005515 protein binding
- GO:0000255 allantoin metabolic process
- GO:0005509 calcium ion binding
- GO:0001553 luteinization
- GO:0001779 natural killer cell differentiation
- GO:0003677 DNA binding
- GO:0003700 sequence-specific DNA binding transcription factor activity
- GO:0004871 signal transducer activity
- GO:0005634 nucleus
- View More GO Terms
- GO:0005737 cytoplasm
- GO:0006101 citrate metabolic process
- GO:0006103 2-oxoglutarate metabolic process
- GO:0006105 succinate metabolic process
- GO:0006107 oxaloacetate metabolic process
- GO:0006549 isoleucine metabolic process
- GO:0006573 valine metabolic process
- GO:0006600 creatine metabolic process
- GO:0006631 fatty acid metabolic process
- GO:0007565 female pregnancy
- GO:0007595 lactation
- GO:0018108 peptidyl-tyrosine phosphorylation
- GO:0019218 regulation of steroid metabolic process
- GO:0019221 cytokine-mediated signaling pathway
- GO:0019530 taurine metabolic process
- GO:0019915 lipid storage
- GO:0030155 regulation of cell adhesion
- GO:0030856 regulation of epithelial cell differentiation
- GO:0032825 positive regulation of natural killer cell differentiation
- GO:0033026 negative regulation of mast cell apoptosis
- GO:0033077 T cell differentiation in thymus
- GO:0040018 positive regulation of multicellular organism growth
- GO:0042104 positive regulation of activated T cell proliferation
- GO:0043029 T cell homeostasis
- GO:0045086 positive regulation of interleukin-2 biosynthetic process
- GO:0045579 positive regulation of B cell differentiation
- GO:0045588 positive regulation of gamma-delta T cell differentiation
- GO:0045647 negative regulation of erythrocyte differentiation
- GO:0045885 positive regulation of survival gene product expression
- GO:0045931 positive regulation of mitotic cell cycle
- GO:0045944 positive regulation of transcription from RNA polymerase II promoter
- GO:0045954 positive regulation of natural killer cell mediated cytotoxicity
- GO:0046449 creatinine metabolic process
- GO:0046543 development of secondary female sexual characteristics
- GO:0046544 development of secondary male sexual characteristics
- GO:0048541 Peyer's patch development
- GO:0050729 positive regulation of inflammatory response
- GO:0060376 positive regulation of mast cell differentiation
- GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway
- GO:0060740 prostate gland epithelium morphogenesis
- GO:0060742 epithelial cell differentiation involved in prostate gland development
- GO:0070668 positive regulation of mast cell proliferation
AHP2413

If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
View all Anti-Mouse ProductsAlways be the first to know.
When we launch new products and resources to help you achieve more in the lab.
Yes, sign me up