NOS-II antibody


Product Details
- Target Species
- Mouse
- Species Cross-Reactivity
-
Target Species Cross Reactivity Rat Human - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Serum - liquid
- Antiserum Preparation
- Antisera to inducible Nitric Oxide Synthase were raised by repeated immunisation of rabbits with highly purified antigen. Whole serum is supplied.
- Preservative Stabilisers
- 0.05% Sodium Azide (NaN3)
- Immunogen
- Mouse macrophage NOS C-terminal peptide (1131-1144) + additional N-terminal Cys conjugated to KLH (CKKGSALEEPKATRL).
Storage Information
- Storage
- Store at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P29477
- Entrez Gene
- Nos2
- GO Terms
- GO:0001666 response to hypoxia
- GO:0004517 nitric-oxide synthase activity
- GO:0005829 cytosol
- GO:0005516 calmodulin binding
- GO:0055114 oxidation-reduction process
- GO:0006527 arginine catabolic process
- GO:0006801 superoxide metabolic process
- GO:0006809 nitric oxide biosynthetic process
- GO:0006954 inflammatory response
- GO:0010181 FMN binding
- GO:0018119 peptidyl-cysteine S-nitrosylation
- GO:0020037 heme binding
- GO:0030863 cortical cytoskeleton
- GO:0034617 tetrahydrobiopterin binding
- GO:0034618 arginine binding
- GO:0042127 regulation of cell proliferation
- GO:0042803 protein homodimerization activity
- GO:0048471 perinuclear region of cytoplasm
- GO:0050660 flavin adenine dinucleotide binding
- GO:0050661 NADP binding
- Regulatory
- For research purposes only
Applications of NOS-II antibody
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Immunohistology - Frozen | 1/500 | ||
Western Blotting | 1/2000 |
Secondary Antibodies Available
Description | Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|---|
Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg |
![]() |
|
Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg |
![]() |
|
Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg |
![]() |
|
Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg |
![]() |
|
Sheep anti Rabbit IgG:FITC | STAR34B | C F | 1 mg |
![]() |
|
Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
![]() |
|
Sheep anti Rabbit IgG:DyLight®488 | STAR36D488GA | F IF WB | 0.1 mg | ||
Sheep anti Rabbit IgG:DyLight®680 | STAR36D680GA | F IF WB | 0.1 mg | ||
Sheep anti Rabbit IgG:Dylight®800 | STAR36D800GA | F IF WB | 0.1 mg |
Useful Reagents Available
Description | Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|---|
TidyBlot Western Blot Detection Reagent:HRP | STAR209P | WB* | 0.5 ml |
Product Specific References
References for NOS-II antibody
-
Lyons, C.R. et al. (1992) Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line.
J Biol Chem. 267 (9): 6370-4. -
Lowenstein, C.J. et al. (1992) Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme.
Proc Natl Acad Sci U S A. 89 (15): 6711-5. -
Bredt, D.S. et al. (1991) Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase.
Nature. 351 (6329): 714-8. -
Hohenstein, B. et al. (2007) Analysis of NO-synthase expression and clinical risk factors in human diabetic
nephropathy.
Nephrol Dial Transplant. 23: 1346-54. -
Fenoglio, C. et al. (2004) Expression of natriuretic peptides, nitric oxide synthase, and guanylate cyclase activity in frog mesonephros during the annual cycle.
Gen Comp Endocrinol. 137: 166-76. -
Elmann, A. et al. (2011) Anti-neuroinflammatory effects of the extract of Achillea fragrantissima.
BMC Complement Altern Med. 11: 98. -
Montes de Oca, M. et al. (2008) Peripheral muscle alterations in non-COPD smokers.
Chest. 133 (1): 13-8. -
Macura, S.L. et al. (2013) Microspheres targeted with a mesothelin antibody and loaded with doxorubicin reduce tumor volume of human mesotheliomas in xenografts.
BMC Cancer. 13: 400. -
Subhan, F. et al. (2017) Fish Scale Collagen Peptides Protect against CoCl2/TNF-α-Induced Cytotoxicity and Inflammation via Inhibition of ROS, MAPK, and NF-κB Pathways in HaCaT Cells.
Oxid Med Cell Longev. 2017: 9703609.
Fluorescent Spectraviewer
Watch the Tool Tutorial Video ▸
How to Use the Spectraviewer?
Watch the Tool Tutorial Video ▸
- Start by selecting the application you are interested in, with the option to select an instrument from the drop down menu or create a customized instrument
- Select the fluorophores or fluorescent proteins you want to include in your panel to check compatibility
- Select the lasers and filters you wish to include
- Select combined or multi-laser view to visualize the spectra