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IgG2c antibody

Goat anti Mouse IgG2c:FITC

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
IgG2c

Product Code Applications Pack Size List Price Your Price Qty
STAR135F
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F 0.5 mg loader
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Goat anti Mouse IgG2c antibody recognizes mouse IgG2c, otherwise known as the Igh 1b allele of IgG2a. Goat anti Mouse IgG2c antibody is assessed by ELISA and immunoelectrophoresis and has been shown to react with IgG2c in C57BL/6, SJL, C57BL/10, CB20, C57BL/6 by Balb/C crosses and pools of serum of outbred mice and does not react with L-chains or other IgG subclasses.

Target Species
Mouse
Product Form
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Preparation
Purified IgG prepared by affinity chromatography.
Antiserum Preparation
Antisera to mouse IgG2c were raised by repeated immunisations of goats with highly purified antigen.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
<0.1% Sodium Azide (NaN3)
0.2% Bovine Serum Albumin
Immunogen
Native mouse IgG2c.
Approx. Protein Concentrations
IgG concentration 1.0mg/ml.
Max Ex/Em
Fluorophore Excitation Max (nm) Emission Max (nm)
FITC 490 525
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.

Store at +4°C. DO NOT FREEZE.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Flow Cytometry
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using the appropriate negative/positive controls.
Flow Cytometry
Use 10μl of the suggested working dilution to label 1x106 cells in 100μl.

References for IgG2c antibody

  1. Jalili, R.B. et al. (2010) Local Expression of Indoleamine 2,3 Dioxygenase in Syngeneic Fibroblasts Significantly Prolongs Survival of an Engineered Three-Dimensional Islet Allograft.
    Diabetes 59: 2219-27
  2. Arnold, I.C. et al. (2011) The C-terminally encoded, MHC class II-restricted T cell antigenicity of the Helicobacter pylori virulence factor CagA promotes gastric preneoplasia.
    J Immunol. 186: 6165-72.
  3. Zouggari, Y. et al. (2013) B lymphocytes trigger monocyte mobilization and impair heart function after acute myocardial infarction.
    Nat Med. 19 (10): 1273-80.
  4. Paes, W. et al. (2016) Recombinant polymorphic membrane protein D in combination with a novel, second-generation lipid adjuvant protects against intra-vaginal Chlamydia trachomatis infection in mice.
    Vaccine. 34 (35): 4123-31.
  5. Carroll, E.C. et al. (2016) The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons.
    Immunity. 44 (3): 597-608.
  6. McEntee, C.P. et al. (2020) Type I IFN signalling is required for cationic adjuvant formulation (CAF)01-induced cellular immunity and mucosal priming.
    Vaccine. 38 (3): 635-43.
  7. Müller-Winkler, J. et al. (2021) Critical requirement for BCR, BAFF, and BAFFR in memory B cell survival.
    J Exp Med. 218 (2) [Epub ahead of print].
  8. Muñoz-Wolf, N. et al. (2023) Non-canonical inflammasome activation mediates the adjuvanticity of nanoparticles.
    Cell Rep Med. 4 (1): 100899.
  9. View The Latest Product References

Synonyms
Igh-1b Allele
RRID
AB_1102667

STAR135F

151071 163224

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