Goat anti Mouse Insulin-Like Growth Factor I antibody recognizes mouse insulin-like growth factor-1 (IGF-1).
IGF-1 stimulates the proliferation of a range of cell types including bone, cartilage tissue and muscle.
- Target Species
- Product Form
- Purified IgG - lyophilised
- Reconstitute with 0.1 ml distilled water
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution. For long term storage the addition of 0.09% sodium azide is recommended.
N.B. For functional studies do not add sodium azide
- Antiserum Preparation
- Antisera to mouse IGF-1 were raised by repeated immunisations of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- None Present
- Carrier Free
- Recombinant mouse IGF-1 (PMP44)
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml after reconstitution
- Prior to reconstitution store at -20°C.
After reconstitution store at -20°C.
This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 6 months from date of despatch
- Entrez Gene
- GO Terms
regulation of protein phosphorylation
blood vessel remodeling
insulin-like growth factor receptor binding
growth factor activity
negative regulation of cell proliferation
glial cell differentiation
positive regulation of gene-specific transcription from RNA polymerase II promoter
positive regulation of glucose import
positive regulation of cerebellar granule cell precursor proliferation
mammary gland development
exocrine pancreas development
regulation of establishment or maintenance of cell polarity
multicellular organism growth
positive regulation of glycogen biosynthetic process
insulin-like growth factor receptor signaling pathway
lung alveolus development
branching morphogenesis of a tube
chondroitin sulfate proteoglycan biosynthetic process
positive regulation of protein kinase B signaling cascade
lung vasculature development
lung lobe morphogenesis
Type I pneumocyte differentiation
Type II pneumocyte differentiation
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
prostate gland growth
prostate gland stromal morphogenesis
negative regulation of androgen receptor signaling pathway
negative regulation of ERK1 and ERK2 cascade
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of IGF-I antibody
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using the appropriate negative/positive controls.
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Secondary Antibodies Available
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