Histone Deacetylase 7 antibody
Rabbit anti histone deacetylase 7 antibody recognizes histone deacetylase 7, also known as HDAC7. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC7 belongs to the class II histone deacetylase/acuc/apha family and has been shown the block MEF2-dependent transcription.
Product Details
- Target Species
- Mouse
- Species Cross-Reactivity
-
Target Species Cross Reactivity Human Expected from Sequence Rat Expected from Sequence - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 30% Glycerol
0.5% Bovine Serum Albumin
0.01% Thiomersal - Immunogen
- Synthetic peptide surrounding amino acid 921 of mouse HDAC7
- Approx. Protein Concentrations
- IgG concentration 0.2 mg/ml
Storage Information
- Storage
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- Q8C2B3
- Entrez Gene
- Hdac7
- GO Terms
- GO:0000118 histone deacetylase complex
- GO:0000122 negative regulation of transcription from RNA polymerase II promoter
- GO:0001570 vasculogenesis
- GO:0003682 chromatin binding
- GO:0003714 transcription corepressor activity
- GO:0004407 histone deacetylase activity
- GO:0005737 cytoplasm
- GO:0006954 inflammatory response
- GO:0007043 cell-cell junction assembly
- GO:0007399 nervous system development
- GO:0016566 specific transcriptional repressor activity
- GO:0016568 chromatin modification
- GO:0030183 B cell differentiation
- GO:0045843 negative regulation of striated muscle tissue development
- Regulatory
- For research purposes only
Applications of Histone Deacetylase 7 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Immunohistology - Paraffin | 20 | 40 ug/ml | |
| Immunoprecipitation | 20 | 40 ug/ml | |
| Western Blotting | 0.5 | 4.0 ug/ml |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti histone deacetylase 7 antibody recognizes a band of approximately 105 kDa in mouse small intestine tissue lysate
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg |
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| Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg |
|
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| Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg |
|
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| Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg |
|
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| Sheep anti Rabbit IgG:FITC | STAR34B | C F | 1 mg |
|
|
| Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
|
|
| Sheep anti Rabbit IgG:DyLight®488 | STAR36D488GA | F IF WB | 0.1 mg | ||
| Sheep anti Rabbit IgG:DyLight®680 | STAR36D680GA | F IF WB | 0.1 mg | ||
| Sheep anti Rabbit IgG:Dylight®800 | STAR36D800GA | F IF WB | 0.1 mg |
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- Select combined or multi-laser view to visualize the spectra
