CD95 / FAS antibody

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Rabbit anti CD95 / FAS

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
AHP2306 P WB 50 µg
Rabbit anti CD95 / FAS antibody recognizes the CD95 antigen, also known as apoptosis-mediating surface antigen Fas and TNFRSF6 (tumor necrosis factor receptor superfamily member 6). Upon ligand binding the Fas receptor forms the death-inducing signaling complex (DISC), which mediates apoptosis.

Product Details

Target Species
Mouse
Species Cross-Reactivity
Target SpeciesCross Reactivity
Human Expected from Sequence
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
30% Glycerol
0.5% Bovine Serum Albumin
0.01% Thiomersal
Immunogen
Synthetic peptide corresponding to residues surrounding amino acid 32 of mouse CD95 / FAS
Approx. Protein Concentrations
IgG concentration 0.5 mg/ml

Storage Information

Storage
Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
12 months from date of despatch

More Information

UniProt
P25446 Related reagents
Entrez Gene
Fas Related reagents
GO Terms
GO:0002377 immunoglobulin production
GO:0003014 renal system process
GO:0016021 integral to membrane
GO:0005576 extracellular region
GO:0006924 activation-induced cell death of T cells
GO:0006925 inflammatory cell apoptosis
GO:0006927 transformed cell apoptosis
GO:0008625 induction of apoptosis via death domain receptors
GO:0009636 response to toxin
GO:0009897 external side of plasma membrane
GO:0010467 gene expression
GO:0019724 B cell mediated immunity
GO:0051260 protein homooligomerization
GO:0043066 negative regulation of apoptosis
GO:0045060 negative thymic T cell selection
GO:0045619 regulation of lymphocyte differentiation
GO:0045637 regulation of myeloid cell differentiation
GO:0048536 spleen development
GO:0050869 negative regulation of B cell activation
GO:0051384 response to glucocorticoid stimulus
GO:0051789 response to protein stimulus
Regulatory
For research purposes only

Applications of CD95 / FAS antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Paraffin 5 ug/ml
Western Blotting 0.5 4.0 ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
Rabbit anti CD95 / Fas antibody recognizes the glycosylated form of CD95 / Fas (approximately 55 kDa), the native form of CD95 / Fas (approximately 35 kDa) and a cleaved CD95 / Fas fragment (approximately 29 kDa) in rat kidney tissue lysate

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Sheep anti Rabbit IgG:Biotin 2AB02B 1 ml C E P WB
Goat anti Rabbit IgG (Fc):Biotin STAR121B 1 mg E WB
Goat anti Rabbit IgG (Fc):FITC STAR121F 1 mg F
Goat anti Rabbit IgG (Fc):HRP STAR121P 1 mg E WB
Goat anti Rabbit IgG (H/L):HRP STAR124P 1 mg C E WB
Sheep anti Rabbit IgG:FITC STAR34B 1 mg C F
Sheep anti Rabbit IgG:RPE STAR35A 1 ml F
Sheep anti Rabbit IgG:DyLight®488 STAR36D488GA 0.1 mg F IF WB
Sheep anti Rabbit IgG:DyLight®549 STAR36D549GA 0.1 mg F IF
Sheep anti Rabbit IgG:DyLight®649 STAR36D649GA 0.1 mg F IF
Sheep anti Rabbit IgG:DyLight®680 STAR36D680GA 0.1 mg F IF WB
Sheep anti Rabbit IgG:Dylight®800 STAR36D800GA 0.1 mg F IF WB