CD193 antibody
CD193 acts as a receptor for eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13) and RANTES (CCL5), the former being a chemoattractant for eosinophils and basophils. CD193 is involved in leukocyte chemotaxis and, along with CD191 (CCR1), is implicated as a regulator of T cell and dendritic cell interaction during the process of antigen presentation. CD193 is implicated as an activator of eosinophils in allergic lung disease, and is a useful TH2 cell marker in monitoring immune responses.
Goat anti Mouse CD193 antibody is reported as suitable for use in immunocytochemistry on acetone fixed cells.
Product Details
- Target Species
- Mouse
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to mouse CD193 (NT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.1% Sodium Azide (NaN3)
0.1% Bovine Serum Albumin - Immunogen
- Synthetic peptide TDEIKTVVESFETTPYEYEWAPPC corresponding to amino acids 5-28 within the N-terminal region of mouse CD193.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
Storage Information
- Storage
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P51678
- Entrez Gene
- Ccr3
- GO Terms
- GO:0005886 plasma membrane
- GO:0001938 positive regulation of endothelial cell proliferation
- GO:0016021 integral to membrane
- GO:0006935 chemotaxis
- GO:0016493 C-C chemokine receptor activity
- GO:0045766 positive regulation of angiogenesis
- Regulatory
- For research purposes only
Applications of CD193 antibody
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Immunohistology - Paraffin 1 | 1/125 | ||
Western Blotting | 1/500 |
- 1This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.Sodium citrate buffer pH 6.0 is recommended for this purpose.
- Histology Positive Control Tissue
- Spleen
Secondary Antibodies Available
Description | Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|---|
Rabbit anti Goat IgG (Fc):FITC | STAR122F | F | 1 mg |
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Rabbit anti Goat IgG (Fc):HRP | STAR122P | C E WB | 1 mg |
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Useful Reagents Available
Description | Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|---|
Antigen Retrieval Buffer, pH8.0 | BUF025A | P | 500 ml | ||
Antigen Retrieval Buffer, pH8.0 | BUF025C | P | 50 ml |
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