c-Jun antibody

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WB ResetRabbit anti c-Jun
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- c-Jun
Rabbit anti c-Jun antibody recognizes c-Jun, also known as p39. The c-Jun transcription factor is encoded by the c-Jun oncogene and dimerizes with c-Fos, JDP and ATF family members to form the AP-1 transcription factor (Eferl and Wagner 2003). AP-1 is activated by a variety of stimuli including cytokines, stress and growth factors, and plays a critical role in cellular processes ranging from proliferation to apoptosis. c-Jun becomes phosphorylated on Serine 63 and Serine 73 by MAPK8 (SAPK/JNK) and PLK3, which regulate c-Jun transcription. c-Jun has been implicated in early tumor development, invasion and metastasis, and due to these findings has been identified as a target for cancer therapies. |
- Target Species
- Mouse
- Species Cross-Reactivity
-
Target Species Cross Reactivity Human Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography
- Antiserum Preparation
- Antiserum to c-Jun was raised by repeated immunisation of rabbits with highly purified antigen
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.1% Sodium Azide (NaN3)
0.2% Gelatin - Immunogen
- Peptide mapping to the amino terminus of mouse c-Jun
- Approx. Protein Concentrations
- IgG concentration 0.2 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Western Blotting | ![]() |
1/400 |
- Western Blotting
- Rabbit anti mouse c-Jun recognizes a band of approximately 36 kDa when run under reducing conditions
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
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Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg |
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Description | Goat anti Rabbit IgG (H/L):HRP | ||||||
Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
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Description | Sheep anti Rabbit IgG:RPE | ||||||
Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg |
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Description | Goat anti Rabbit IgG (Fc):Biotin | ||||||
Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg |
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Description | Goat anti Rabbit IgG (Fc):FITC | ||||||
Sheep anti Rabbit IgG:FITC | STAR34B | C F | 1 mg |
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Description | Sheep anti Rabbit IgG:FITC | ||||||
Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg |
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Description | Goat anti Rabbit IgG (Fc):HRP |
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
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TidyBlot Western Blot Detection Reagent:HRP | STAR209P | WB* | 0.5 ml | Log in | |||
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Description | TidyBlot Western Blot Detection Reagent:HRP |
- Synonyms
- AP-1
- p39
- UniProt
- P05627
- Entrez Gene
- Jun
- GO Terms
- GO:0051726 regulation of cell cycle
- GO:0005667 transcription factor complex
- GO:0008285 negative regulation of cell proliferation
- GO:0042493 response to drug
- GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
- GO:0010843 promoter binding
- GO:0017053 transcriptional repressor complex
- GO:0031953 negative regulation of protein autophosphorylation
- GO:0035026 leading edge cell differentiation
- View More GO Terms
- GO:0048146 positive regulation of fibroblast proliferation
- GO:0071277 cellular response to calcium ion
AHP2412

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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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