Rabbit anti XAF1 antibody recognizes the X-linked inhibitor of apoptosis (XIAP)-associated factor 1 (XAF1). XAF1 is normally expressed in all adult and fetal tissues, the levels of XAF1 has been shown to be inversely correlated with p53. p53 is, in turn, directly responsible for inhibiting XAF1 transcription. Overexpression of XAF1 may result in the neutralization of XIAP’s, which are inhibitors of apoptosis. They may therefore inhibit the ability to promote cell death.
- Target Species
- Product Form
- Purified IgG - liquid
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 30% Glycerol
0.5% Bovine Serum Albumin
- Synthetic peptide surrounding a.a. 306 of human XAF1
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of XAF1 antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti XAF1 antibody recognizes a band of approximately 34 kDa in Jurkat lysates
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Secondary Antibodies Available