WNT-4 antibody

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Rabbit anti WNT-4

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
AHP2360 WB 50 µg
Rabbit anti WNT-4 antibody recognizes protein Wnt-4 which promotes female sex development and represses male sex development. It plays a role in both the control of female development and the prevention of testes formation. It also regulates endometrial stromal cell proliferation, survival, and differentiation, all processes which are necessary for the development of an embryo.

Product Details

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse Expected from Sequence
Rat Expected from Sequence
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
30% Glycerol
0.5% Bovine Serum Albumin
0.01% Thiomersal
Immunogen
Synthetic peptide surrounding amino acid 10 of human WNT-4
Approx. Protein Concentrations
IgG concentration 0.5 mg/ml

Storage Information

Storage
Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
12 months from date of despatch

More Information

UniProt
P56705 Related reagents
Entrez Gene
WNT4 Related reagents
GO Terms
GO:0005886 plasma membrane
GO:0001658 branching involved in ureteric bud morphogenesis
GO:0001837 epithelial to mesenchymal transition
GO:0001889 liver development
GO:0003714 transcription corepressor activity
GO:0004871 signal transducer activity
GO:0007223 Wnt receptor signaling pathway, calcium modulating pathway
GO:0005201 extracellular matrix structural constituent
GO:0005578 proteinaceous extracellular matrix
GO:0005615 extracellular space
GO:0005794 Golgi apparatus
GO:0006702 androgen biosynthetic process
GO:0007492 endoderm development
GO:0008584 male gonad development
GO:0008585 female gonad development
GO:0009798 axis specification
GO:0009952 anterior/posterior pattern formation
GO:0009986 cell surface
GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
GO:0016563 transcription activator activity
GO:0018345 protein palmitoylation
GO:0030237 female sex determination
GO:0030325 adrenal gland development
GO:0030501 positive regulation of bone mineralization
GO:0032349 positive regulation of aldosterone biosynthetic process
GO:0032967 positive regulation of collagen biosynthetic process
GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway
GO:0043193 positive regulation of gene-specific transcription
GO:0045669 positive regulation of osteoblast differentiation
GO:0048599 oocyte development
GO:0051145 smooth muscle cell differentiation
GO:0060070 canonical Wnt receptor signaling pathway
GO:0060126 somatotropin secreting cell differentiation
GO:0060129 thyroid-stimulating hormone-secreting cell differentiation
GO:0060748 tertiary branching involved in mammary gland duct morphogenesis
GO:0061054 dermatome development
GO:0061205 paramesonephric duct development
GO:0061369 negative regulation of testicular blood vessel morphogenesis
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:0072033 renal vesicle formation
GO:0072162 metanephric mesenchymal cell differentiation
GO:0072164 mesonephric tubule development
GO:0090002 establishment of protein localization in plasma membrane
GO:0090090 negative regulation of canonical Wnt receptor signaling pathway
GO:0090263 positive regulation of canonical Wnt receptor signaling pathway
GO:2000019 negative regulation of male gonad development
GO:2000066 positive regulation of cortisol biosynthetic process
GO:2000225 negative regulation of testosterone biosynthetic process
Regulatory
For research purposes only

Applications of WNT-4 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 0.5 4.0 ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
Rabbit anti WNT-4 antibody recognizes a band of approximately 39 kDa in Jurkat lysates

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Sheep anti Rabbit IgG:Biotin 2AB02B 1 ml C E P WB
Goat anti Rabbit IgG (Fc):Biotin STAR121B 1 mg E WB
Goat anti Rabbit IgG (Fc):FITC STAR121F 1 mg F
Goat anti Rabbit IgG (Fc):HRP STAR121P 1 mg E WB
Goat anti Rabbit IgG (H/L):HRP STAR124P 1 mg C E WB
Sheep anti Rabbit IgG:FITC STAR34B 1 mg C F
Sheep anti Rabbit IgG:RPE STAR35A 1 ml F
Sheep anti Rabbit IgG:DyLight®488 STAR36D488GA 0.1 mg F IF WB
Sheep anti Rabbit IgG:DyLight®549 STAR36D549GA 0.1 mg F IF
Sheep anti Rabbit IgG:DyLight®649 STAR36D649GA 0.1 mg F IF
Sheep anti Rabbit IgG:DyLight®680 STAR36D680GA 0.1 mg F IF WB
Sheep anti Rabbit IgG:Dylight®800 STAR36D800GA 0.1 mg F IF WB