WNT-1 antibody

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Rabbit anti WNT-1

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
AHP2359 WB 50 µg
Rabbit anti WNT-1 antibody recognizes wingless-type MMTV integration site family, member 1 (WNT-1). This protein is highly conserved in evolution and is essential for normal development of the embryonic nervous system. It contributes to hyperplasia and tumorigenic progression when improperly expressed in mammary tissue and is associated with osteogenesis imperfecta type XV and osteoporosis.

Product Details

Target Species
Human
Product Form
Purified IgG - liquid
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
30% Glycerol
0.5% Bovine Serum Albumin
0.01% Thiomersal
Immunogen
Synthetic peptide surrounding amino acid 31 of human WNT-1
Approx. Protein Concentrations
IgG concentration 0.5 mg/ml

Storage Information

Storage
Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
12 months from date of despatch

More Information

UniProt
P04628 Related reagents
Entrez Gene
WNT1 Related reagents
GO Terms
GO:0005886 plasma membrane
GO:0004871 signal transducer activity
GO:0007223 Wnt receptor signaling pathway, calcium modulating pathway
GO:0005109 frizzled binding
GO:0005110 frizzled-2 binding
GO:0005578 proteinaceous extracellular matrix
GO:0005615 extracellular space
GO:0005769 early endosome
GO:0005770 late endosome
GO:0009611 response to wounding
GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
GO:0010592 positive regulation of lamellipodium assembly
GO:0010812 negative regulation of cell-substrate adhesion
GO:0010843 promoter binding
GO:0016563 transcription activator activity
GO:0021536 diencephalon development
GO:0021551 central nervous system morphogenesis
GO:0021588 cerebellum formation
GO:0021592 fourth ventricle development
GO:0021797 forebrain anterior/posterior pattern formation
GO:0022004 midbrain-hindbrain boundary maturation during brain development
GO:0022408 negative regulation of cell-cell adhesion
GO:0030901 midbrain development
GO:0033077 T cell differentiation in thymus
GO:0035284 brain segmentation
GO:0042472 inner ear morphogenesis
GO:0042770 signal transduction in response to DNA damage
GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway
GO:0044336 canonical Wnt receptor signaling pathway involved in negative regulation of apoptosis
GO:0045121 membrane raft
GO:0045599 negative regulation of fat cell differentiation
GO:0045747 positive regulation of Notch signaling pathway
GO:0048146 positive regulation of fibroblast proliferation
GO:0048332 mesoderm morphogenesis
GO:0048664 neuron fate determination
GO:0061054 dermatome development
GO:0070365 hepatocyte differentiation
GO:0071425 hemopoietic stem cell proliferation
GO:2000002 negative regulation of DNA damage checkpoint
Regulatory
For research purposes only

Applications of WNT-1 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 0.5 4.0 ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
Rabbit anti WNT-1 antibody recognizes a band of approximately 41 kDa in Jurkat lysates

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Sheep anti Rabbit IgG:Biotin 2AB02B 1 ml C E P WB
Goat anti Rabbit IgG (Fc):Biotin STAR121B 1 mg E WB
Goat anti Rabbit IgG (Fc):FITC STAR121F 1 mg F
Goat anti Rabbit IgG (Fc):HRP STAR121P 1 mg E WB
Goat anti Rabbit IgG (H/L):HRP STAR124P 1 mg C E WB
Sheep anti Rabbit IgG:FITC STAR34B 1 mg C F
Sheep anti Rabbit IgG:RPE STAR35A 1 ml F
Sheep anti Rabbit IgG:DyLight®488 STAR36D488GA 0.1 mg F IF WB
Sheep anti Rabbit IgG:DyLight®549 STAR36D549GA 0.1 mg F IF
Sheep anti Rabbit IgG:DyLight®649 STAR36D649GA 0.1 mg F IF
Sheep anti Rabbit IgG:DyLight®680 STAR36D680GA 0.1 mg F IF WB
Sheep anti Rabbit IgG:Dylight®800 STAR36D800GA 0.1 mg F IF WB