Wasp antibody
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WB ResetRabbit anti WASP
- Product Type
- PrecisionAb Polyclonal
- Isotype
- Polyclonal IgG
- Format
- Purified
- Specificity
- Wasp
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| Rabbit anti Human WASP antibody recognizes WASP, also known as eczema-thrombocytopenia, thrombocytopenia 1 (X-linked) and wiskott-Aldrich syndrome protein. The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. WAS proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome, due to mutatations in the WAS gene, is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia. The WAS gene product (WASP) is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signaling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5′ UTR sequence, has been described (provided by RefSeq, Jul 2008). Rabbit anti Human WASP antibody detects a band of 60 kDa. Rabbit anti Human WASP antibody has been extensively validated for western blotting using whole cell lysates. |
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- Target Species
- Human
- Western Blotting
- Anti WASP detects a band of approximately 60 kDa in Ramos cell lysate.
- Product Form
- Purified IgG - liquid
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline.
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3).
- Immunogen
- KLH-conjugated synthetic peptide corresponding to aa 205-234 of human WASP
- Regulatory
- For research purposes only.
- Guarantee
- 12 months from date of despatch.
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Goat anti Rabbit IgG (H/L):HRP | STAR208P | WB | 2 ml | Log in | |||
| List Price | Your Price | ||||||
| Log in | |||||||
| Description | Goat anti Rabbit IgG (H/L):HRP | ||||||
- UniProt
- P42768
- Entrez Gene
- WAS
- GO Terms
- GO:0006952 defense response
- GO:0007596 blood coagulation
- GO:0005829 cytosol
- GO:0005083 small GTPase regulator activity
- GO:0006955 immune response
- GO:0008544 epidermis development
- GO:0042802 identical protein binding
- GO:0015629 actin cytoskeleton
- GO:0050852 T cell receptor signaling pathway
- View More GO Terms
View more products with Wasp specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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