Vitamin D Receptor antibody
Product Details
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Rat Mouse Dog Expected from Sequence - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antisera to human Vitamin D receptor were raised by repeated immunisations of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- TRIS buffered saline
- Preservative Stabilisers
0.02% Sodium Azide 0.5% Bovine Serum Albumin - Immunogen
- Peptide sequence CGNQDYKYRVSD corresponding to the internal region of Vitamin D receptor (NP_000367.1).
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
Storage Information
- Storage
- Store at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P11473
- Entrez Gene
- VDR
- GO Terms
- GO:0003700 sequence-specific DNA binding transcription factor activity
- GO:0003707 steroid hormone receptor activity
- GO:0005654 nucleoplasm
- GO:0008270 zinc ion binding
- GO:0008285 negative regulation of cell proliferation
- GO:0008434 vitamin D3 receptor activity
- GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
- GO:0010980 positive regulation of vitamin D 24-hydroxylase activity
- GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
- GO:0046697 decidualization
- GO:0046965 retinoid X receptor binding
- GO:0060558 regulation of calcidiol 1-monooxygenase activity
- Regulatory
- For research purposes only
Applications of Vitamin D Receptor antibody
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA | 1/16,000 | ||
Western Blotting | 0.3 | 1.0ug/ml |
- Western Blotting
- AHP1093 detects a band of approximately 40-45kDa in human brain cell lysates. A minimum incubation time of 1 hour is recommended with this antibody.
Secondary Antibodies Available
Description | Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|---|
Rabbit anti Goat IgG (Fc):FITC | STAR122F | F | 1 mg |
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Rabbit anti Goat IgG (Fc):HRP | STAR122P | C E WB | 1 mg |
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Product Specific References
References for Vitamin D Receptor antibody
-
Cheng, H.T. et al. (2006) Functional role of VDR in the activation of p27Kip1 by the VDR/Sp1 complex.
J Cell Biochem. 98 (6): 1450-6.
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