Rabbit anti Human VEGF receptor 1 antibody recognizes the extracellular (N-terminal) domain of human Vascular Endothelial Growth Factor Receptor 1, also known as VEGFR1 or Flt-1. VEGFR1 is a ~180 kDa membrane receptor tyrosine kinase. It is expressed by almost all vascular endothelial cell and some peripheral blood monocytes. Vascular Endothelial Growth Factor is a regulator of physiological angiogenesis during embryogenesis, skeletal growth and reproductive functions.
- Target Species
- Species Cross-Reactivity
|Target Species||Cross Reactivity|
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Serum - liquid
- Antiserum Preparation
- Antisera to human VEGF receptor 1 were raised by repeated immunisations of rabbits with highly purified antigen.
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
0.5% Bovine Serum Albumin
- Peptide corresponding to the N-terminal (extracellular) domain of human VEGF receptor 1.
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 18 months from date of despatch.
- Entrez Gene
- GO Terms
growth factor binding
vascular endothelial growth factor receptor activity
integral to plasma membrane
positive regulation of vascular endothelial growth factor receptor signaling pathway
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of VEGF Receptor 1 antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- AHP1600 detects a band of approximately 75kDa in human endothelial cell lysate.
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Secondary Antibodies Available
Useful Reagents Available