VDAC1 antibody

Rabbit anti VDAC1

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
VDAC1

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VPA00169
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Rabbit anti Human VDAC1 antibody recognizes the voltage-dependent anion-selective channel protein 1, also known as outer mitochondrial membrane protein porin 1, plasmalemmal porin, porin 31HL, porin 31HM and voltage-dependent anion-selective channel protein 1.

VDAC1 is a voltage-dependent anion channel protein and a major component of the outer mitochondrial membrane. This protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. It also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of VDAC1 are found on chromosomes 1, 2 3, 6, 9, 12, X and Y (provided by RefSeq, Sep 2010).

Rabbit anti Human VDAC1 antibody detects a band of 32 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti VDAC1 detects a band of approximately 32 kDa in Jurkat cell lysates.
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3).
Immunogen
Synthetic peptide corresponding to amino acids 185-197 of human VDAC1
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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UniProt
P21796
Entrez Gene
VDAC1
GO Terms
GO:0005886 plasma membrane
GO:0005515 protein binding
GO:0006915 apoptosis
GO:0005741 mitochondrial outer membrane
GO:0008308 voltage-gated anion channel activity
GO:0015288 porin activity
GO:0046930 pore complex
GO:0042645 mitochondrial nucleoid
GO:0044419 interspecies interaction between organisms
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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