VDAC1 is a voltage-dependent anion channel protein and a major component of the outer mitochondrial membrane. This protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. It also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of VDAC1 are found on chromosomes 1, 2 3, 6, 9, 12, X and Y (provided by RefSeq, Sep 2010).
Rabbit anti Human VDAC1 antibody detects a band of 32 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
- Target Species
- Western Blotting
- Anti VDAC1 detects a band of approximately 32 kDa in Jurkat cell lysates.
- Species Cross-Reactivity
Target Species Cross Reactivity Mouse Rat
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Rabbit polyclonal antibody purified by affinity chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Synthetic peptide corresponding to amino acids 185-197 of human VDAC1
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
- GO:0005886 plasma membrane
- GO:0005515 protein binding
- GO:0006915 apoptosis
- GO:0005741 mitochondrial outer membrane
- GO:0008308 voltage-gated anion channel activity
- GO:0015288 porin activity
- GO:0046930 pore complex
- GO:0042645 mitochondrial nucleoid
- GO:0044419 interspecies interaction between organisms
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- For research purposes only
Applications of VDAC1 antibody
|Application Name||Verified||Min Dilution||Max Dilution|
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
Secondary Antibodies Available
|Description||Product Code||Applications||Pack Size||List Price||Quantity|
|Goat anti Rabbit IgG (H/L):HRP||STAR208P||WB||2 ml|
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