Urokinase antibody



A specific polymorphism in the gene encoding uPA may be associated with late-onset Alzheimer's disease (Ertekin-Taner et al. 2005). The levels of uPA, uPAR and its soluble fragments have also been found to be increased in tissues, plasma and other body fluids of cancer patients and to be markers of cancer development and metastasis (Kim et al. 2016).
Product Details
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antisera to Urokinase were raised by repeated immunisations of goat with highly purified antigen. Purified IgG prepared by affinity chromatography.
- Buffer Solution
- TRIS buffered saline
- Preservative Stabilisers
0.02% Sodium Azide (NaN3) 0.5% Bovine Serum Albumin - Immunogen
- Peptide with sequence C-HFLPWIRSHTKEEN from the C-terminal of the Urokinase sequence.
- Approx. Protein Concentrations
- IgG concentration 0.5mg/ml
Storage Information
- Storage
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P00749
- Entrez Gene
- PLAU
- GO Terms
- GO:0005886 plasma membrane
- GO:0004252 serine-type endopeptidase activity
- GO:0007596 blood coagulation
- GO:0007165 signal transduction
- GO:0005615 extracellular space
- GO:0006508 proteolysis
- GO:0006935 chemotaxis
- GO:0009986 cell surface
- GO:0010469 regulation of receptor activity
- GO:0014910 regulation of smooth muscle cell migration
- GO:0033628 regulation of cell adhesion mediated by integrin
- GO:0042730 fibrinolysis
- GO:2000097 regulation of smooth muscle cell-matrix adhesion
- Regulatory
- For research purposes only
Applications of Urokinase antibody
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA | 1/8000 | ||
Western Blotting | 0.3 | 1.0ug/ml |
- Western Blotting
- AHP1065 detects a band of approximately 48kDa in KEH 293 cell lysates.
Secondary Antibodies Available
Description | Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|---|
Rabbit anti Goat IgG (Fc):FITC | STAR122F | F | 1 mg |
![]() |
|
Rabbit anti Goat IgG (Fc):HRP | STAR122P | C E WB | 1 mg |
![]() |
Product Specific References
References for Urokinase antibody
-
Mondino, A. & Blasi, F. (2004) uPA and uPAR in fibrinolysis, immunity and pathology.
Trends Immunol. 25 (8): 450-5. -
Danø, K. et al. (2005) Plasminogen activation and cancer.
Thromb Haemost. 93 (4): 676-81.
Fluorescent Spectraviewer
Watch the Tool Tutorial Video ▸
How to Use the Spectraviewer?
Watch the Tool Tutorial Video ▸
- Start by selecting the application you are interested in, with the option to select an instrument from the drop down menu or create a customized instrument
- Select the fluorophores or fluorescent proteins you want to include in your panel to check compatibility
- Select the lasers and filters you wish to include
- Select combined or multi-laser view to visualize the spectra