TSLP Receptor antibody
Rabbit anti Human TSLP receptor antibody recognizes human thymic stromal lymphopoietin receptor (TSLPR), a 42 kDa glycoprotein belonging to the type 1 cytokine receptor family. TSLPR is primarily expressed by dendritic cells and monocytes, and weakly expressed by T-cells. It is also expressed by non-haematopoietic tissues such as the heart, skeletal muscle, kidney and liver.
The TSLP receptor forms functional complexes with thymic stromal lymphopoietin (TSLP) and IL-7R, which are capable of stimulating cell proliferation through activation of Stat3 and Stat5.
The TSLP receptor forms functional complexes with thymic stromal lymphopoietin (TSLP) and IL-7R, which are capable of stimulating cell proliferation through activation of Stat3 and Stat5.
Product Details
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Antisera to human TSLP receptor were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.02% Sodium Azide - Immunogen
- A 19 amino acid peptide located near the centre of human TSLP recptor.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
Storage Information
- Storage
- Store at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 18 months from date of despatch.
More Information
- UniProt
- Q9HC73
- Entrez Gene
- CRLF2
- GO Terms
- GO:0005886 plasma membrane
- GO:0016021 integral to membrane
- GO:0005576 extracellular region
- GO:0004872 receptor activity
- Regulatory
- For research purposes only
Applications of TSLP Receptor antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Immunohistology - Paraffin 1 | |||
| Western Blotting | 0.5 | 1.0ug/ml |
- 1This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
- Western Blotting
- AHP1431 detects a band of approximately 53kDa in human liver tissue cell lysates.
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg |
|
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| Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg |
|
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| Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg |
|
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| Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg |
|
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| Sheep anti Rabbit IgG:FITC | STAR34B | C F | 1 mg |
|
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| Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
|
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| Sheep anti Rabbit IgG:DyLight®488 | STAR36D488GA | F IF WB | 0.1 mg | ||
| Sheep anti Rabbit IgG:DyLight®680 | STAR36D680GA | F IF WB | 0.1 mg | ||
| Sheep anti Rabbit IgG:Dylight®800 | STAR36D800GA | F IF WB | 0.1 mg |
Useful Reagents Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Antigen Retrieval Buffer, pH8.0 | BUF025A | P | 500 ml | ||
| Antigen Retrieval Buffer, pH8.0 | BUF025C | P | 50 ml | ||
| TidyBlot Western Blot Detection Reagent:HRP | STAR209P | WB* | 0.5 ml |
Product Specific References
References for TSLP Receptor antibody
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Sun M et al. (2014) In situ expression and serum level of thymic stromal lymphopoietin in oral lichen planus.
J Oral Pathol Med. 43 (10): 740-5.
Further Reading
-
Park, L.S. et al. (2000) Cloning of the murine thymic stromal lymphopoietin (TSLP) receptor: Formation of a functional heteromeric complex requires interleukin 7 receptor.
J Exp Med. 192 (5): 659-70.
