TSLP Receptor antibody

Rabbit anti Human TSLP Receptor

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
TSLP Receptor

Product Code Applications Pack Size List Price Your Price Qty
AHP1431
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SDS Safety Datasheet SDS
P * WB 0.1 mg loader
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Rabbit anti Human TSLP receptor antibody recognizes human thymic stromal lymphopoietin receptor (TSLPR), a 42 kDa glycoprotein belonging to the type 1 cytokine receptor family. TSLPR is primarily expressed by dendritic cells and monocytes, and weakly expressed by T-cells. It is also expressed by non-haematopoietic tissues such as the heart, skeletal muscle, kidney and liver.

The TSLP receptor forms functional complexes with thymic stromal lymphopoietin (TSLP) and IL-7R, which are capable of stimulating cell proliferation through activation of Stat3 and Stat5.

Target Species
Human
Product Form
Purified IgG - liquid
Preparation
Antisera to human TSLP receptor were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.02%Sodium Azide
Immunogen
A 19 amino acid peptide located near the centre of human TSLP recptor.
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Paraffin 1
Western Blotting 0.5 1.0ug/ml
  1. 1This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
Western Blotting
AHP1431 detects a band of approximately 53kDa in human liver tissue cell lysates.

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Description TidyBlot Western Blot Detection Reagent:HRP

References for TSLP Receptor antibody

  1. Sun M et al. (2014) In situ expression and serum level of thymic stromal lymphopoietin in oral lichen planus.
    J Oral Pathol Med. 43 (10): 740-5.

Further Reading

  1. Park, L.S. et al. (2000) Cloning of the murine thymic stromal lymphopoietin (TSLP) receptor: Formation of a functional heteromeric complex requires interleukin 7 receptor.
    J Exp Med. 192 (5): 659-70.

Synonyms
Cytokine RECEPTOR-LIKE 2
RRID
AB_1102914
UniProt
Q9HC73
Entrez Gene
CRLF2
GO Terms
GO:0005886 plasma membrane
GO:0016021 integral to membrane
GO:0005576 extracellular region
GO:0004872 receptor activity
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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