TSLP antibody

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P ResetRabbit anti Human TSLP
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- TSLP
Rabbit anti Human TSLP antibody recognizes human TSLP (thymic stromal lymphopoietin), a 132 amino acid secreted haemopoietic cytokine which shares biological properties with interleukin-7 (IL-7), including involvement in B-cell development, and the activation and phosphorylation of STAT3 and STAT5. TSLP is expressed in the heart, liver and prostate and functions through binding to a receptor complex consisting of the TSLPR (thymic stromal lymphopoietin receptor) and the IL-7R alpha chain. Properties attributed to TSLP include the induction of monocytes to release T cell-attracting chemokines, enhancing the maturation of CD11c+ dendritic cells and their ability to stimulate T cells, and strong evidence suggests that TSLP plays a pivotal role in allergic immune responses. |
- Target Species
- Human
- Product Form
- Purified IgG - lyophilized
- Reconstitution
- Reconstitute with 0.1ml distilled water.
For long term storage the addition of 0.09% sodium azide is recommended. - Antiserum Preparation
- Antisera to human TSLP were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- None present
- Carrier Free
- Yes
- Immunogen
- Recombinant human TSLP.
- Approx. Protein Concentrations
- IgG concentration 1.0mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
After reconstitution store at -20°C.
This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA | ![]() |
0.5 | 2.0ug/ml |
Immunohistology - Paraffin 1 | ![]() |
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Western Blotting | ![]() |
0.1 | 0.2ug/ml |
- 1 This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.
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Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
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Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg |
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Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg |
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Sheep anti Rabbit IgG:FITC | STAR34B | C F | 1 mg |
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Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg |
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Description | Goat anti Rabbit IgG (Fc):HRP |
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Antigen Retrieval Buffer, pH8.0 | BUF025A | P | 500 ml | Log in | |||
List Price | Your Price | ||||||
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Description | Antigen Retrieval Buffer, pH8.0 | ||||||
TidyBlot Western Blot Detection Reagent:HRP | STAR209P | WB* | 0.5 ml | Log in | |||
List Price | Your Price | ||||||
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Description | TidyBlot Western Blot Detection Reagent:HRP |
Further Reading
-
Liu, Y.J. et al. (2007) TSLP: an epithelial cell cytokine that regulates T cell differentiation by conditioning dendritic cell maturation.
Annu Rev Immunol. 25: 193-219.
- Synonyms
- Thymic Stromal Lymphopoietin
- RRID
- AB_2287808
- UniProt
- Q969D9
- Entrez Gene
- TSLP
- GO Terms
- GO:0005125 cytokine activity
- GO:0005615 extracellular space
AHP1286


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