TREX1 antibody

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Anti TREX1 Antibody (PrecisionAb Polyclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with TREX1 antibody followed by detection with HRP conjugated Goat anti Rabbit IgG (1/10,000, STAR208P) and visualized on the ChemiDoc MP with 120 second exposure. Arrow points to TREX1 (molecular weight 33 kDa)

Rabbit anti TREX1

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified
Specificity: TREX1

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VPA00944 Datasheet Datasheet SDS SDS	WB	100 µl		Log in	Get Quote
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Rabbit anti Human TREX1 antibody recognizes TREX1, also known as 3' repair exonuclease 1, 3'-5' exonuclease TREX1, DNase III and three-prime repair exonuclease 1.

TREX1 encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. Mutations in TREX1 result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants (provided by RefSeq, Sep 2012).

Rabbit anti Human TREX1 antibody detects a band of 33 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Target Species: Human
Western Blotting: Anti TREX1 antibody recognizes a band of approximately 33 kDa in Raji cell lysates
Species Cross-Reactivity: Target Species Cross Reactivity

Mouse; N.B. Antibody reactivity and working conditions may vary between species.
Product Form: Purified IgG - liquid
Preparation: Rabbit polyclonal antibody purified by affinity chromatography on immunogen
Buffer Solution: Phosphate buffered saline
Preservative Stabilisers: 0.09% Sodium Azide
<50% Glycerol
Immunogen: Recombinant protein of human TREX1
Regulatory: For research purposes only
Guarantee: 12 months from date of despatch
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories

Target Species	Cross Reactivity
Mouse

Store undiluted at -20°C, avoiding repeated freeze thaw cycles

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting			1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description	Product Code	Applications	Pack Size	Your Price
Goat anti Rabbit IgG (H/L):HRP	STAR208P	WB	2 ml	Log in	Get Quote
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Description	Goat anti Rabbit IgG (H/L):HRP

UniProt: Q9NSU2
Entrez Gene: TREX1
GO Terms: GO:0006260 DNA replication; GO:0003697 single-stranded DNA binding; GO:0046872 metal ion binding; GO:0005635 nuclear envelope; GO:0006298 mismatch repair; GO:0006310 DNA recombination; GO:0008219 cell death; GO:0008296 3'-5'-exodeoxyribonuclease activity; GO:0008853 exodeoxyribonuclease III activity; View More GO Terms; GO:0032405 MutLalpha complex binding; GO:0032407 MutSalpha complex binding; GO:0042803 protein homodimerization activity