Rabbit anti TRADD antibody recognizes tumor necrosis factor receptor type 1-associated DEATH domain protein that in humans is encoded by the TRADD gene. The protein encoded by this gene is a death domain containing an adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation.
- Target Species
- Species Cross-Reactivity
|Target Species||Cross Reactivity|
||Expected from Sequence
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 30% Glycerol
0.5% Bovine Serum Albumin
- Synthetic peptide surrounding amino acid 300 of human TRADD
- Approx. Protein Concentrations
- IgG concentration 0.2 mg/ml
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
signal transducer activity
activation of caspase activity
induction of apoptosis by extracellular signals
activation of pro-apoptotic gene products
identical protein binding
intermediate filament binding
tumor necrosis factor-mediated signaling pathway
positive regulation of I-kappaB kinase/NF-kappaB cascade
death domain binding
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of TRADD antibody
|Immunohistology - Paraffin
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti TRADD antibody recognizes a band of approximately 34 kDa in mouse small intestine lysates
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Secondary Antibodies Available
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