TIMP-2 antibody

Sheep anti Human TIMP-2 (Loop 6)

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
TIMP-2
Region
(LOOP 6)

Product Code Applications Pack Size List Price Your Price Qty
9013-2609
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
C IF IP WB 1 ml
List Price Your Price
Search for Batch Specific Datasheets

Sheep anti Human TIMP-2 antibody recognizes human TIMP-2, a tissue inhibitor that complexes with and irreversibly inactivates various metalloproteinases.

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Rat
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein G
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
Synthetic peptide corresponding to the loop 6 region of the native molecule conjugated to Keyhole Limpet Haemocyanin.
Approx. Protein Concentrations
IgG concentration 5.0 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunofluorescence
Immunohistology - Frozen
Immunoprecipitation
Western Blotting
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.

Description Product Code Applications Pack Size List Price Your Price Quantity
Rabbit anti Sheep IgG (H/L):Biotin 5184-2304 C E F WB 1.5 ml loader
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Description Rabbit anti Sheep IgG (H/L):Biotin
Donkey anti Sheep/Goat IgG:DyLight®488 STAR88D488GA F IF 0.1 mg loader
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Description Donkey anti Sheep/Goat IgG:DyLight®488
Donkey anti Sheep/Goat IgG:HRP STAR88P C E P WB 1 ml loader
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loader
Description Donkey anti Sheep/Goat IgG:HRP

References for TIMP-2 antibody

  1. Chu, S.C. et al. (2004) Silibinin inhibits the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2.
    Mol Carcinog. 40 (3): 143-9.
  2. Chen, P.N. et al. (2006) Mulberry anthocyanins, cyanidin 3-rutinoside and cyanidin 3-glucoside, exhibited an inhibitory effect on the migration and invasion of a human lung cancer cell line.
    Cancer Lett. 235 (2): 248-59.
  3. Ho, M.L. et al. (2011) Antimetastatic Potentials of Dioscorea nipponica on Melanoma In Vitro and In Vivo
    Evidence-Based Complementary and Alternative Medicine 2011 Article ID 507920
  4. Jaworski, D.M. et al. (2011) Sexually dimorphic diet-induced insulin resistance in obese tissue inhibitor of metalloproteinase-2 (TIMP-2)-deficient mice.
    Endocrinology. 152 (4): 1300-13.

Western Blotting

RRID
AB_620423
UniProt
P16035
Entrez Gene
TIMP2
GO Terms
GO:0046872 metal ion binding
GO:0008191 metalloendopeptidase inhibitor activity
View more products with TIMP-2 specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Human Products