TBX1 antibody

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Anti TBX1 Antibody (PrecisionAb Polyclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with TBX1 antibody followed by detection with HRP conjugated Goat anti Rabbit IgG (1/10,000, STAR208P) and visualized on the ChemiDoc MP with 12 second exposure. Arrow points to TBX1 (molecular weight 43 kDa)

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Rabbit anti TBX1

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified
Specificity: TBX1

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Rabbit anti Human TBX1 antibody recognizes the T-box transcription factor TBX1, also known as T-box 1 transcription factor C, TGA, CAFS or VCF.

The TBX1 gene is a member of a phylogenetically conserved family of genes sharing a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. TBX1 product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS) and velocardiofacial syndrome (VCFS), common congenital disorders characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where TBX1 has been mapped. Mouse models of DiGeorge syndrome suggest a major role for TBX1 in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for TBX1 (provided by RefSeq, Jul 2008).

Rabbit anti Human TBX1 antibody detects a band of 43 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Target Species: Human
Western Blotting: Rabbit anti TBX1 detects a band of approximately 43 kDa in MCF7 cell lysates.
Product Form: Purified IgG - liquid
Preparation: Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution: Phosphate buffered saline.
Preservative Stabilisers: 0.09% Sodium Azide
2% Sucrose
Immunogen: Synthetic peptide encompassing part of the middle region of human TBX1
Regulatory: For research purposes only.
Guarantee: 12 months from date of despatch.
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting			1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description	Product Code	Applications	Pack Size	Your Price
Goat anti Rabbit IgG (H/L):HRP	STAR208P	WB	2 ml	Log in	Get Quote
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Description	Goat anti Rabbit IgG (H/L):HRP

UniProt: O43435
Entrez Gene: TBX1
GO Terms: GO:0003700 sequence-specific DNA binding transcription factor activity; GO:0003702 RNA polymerase II transcription factor activity; GO:0005634 nucleus; GO:0006357 regulation of transcription from RNA polymerase II promoter; GO:0007507 heart development; GO:0042803 protein homodimerization activity; GO:0043565 sequence-specific DNA binding; GO:0048538 thymus development; GO:0048703 embryonic viscerocranium morphogenesis; View More GO Terms; GO:0060017 parathyroid gland development; GO:0060023 soft palate development; GO:0060037 pharyngeal system development