Tamm Horsfall Glycoprotein antibody









Product Details
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- IgG fraction - liquid
- Preparation
- IgG fraction prepared by anion exchange chromatography
- Buffer Solution
- Glycine buffered saline
- Preservative Stabilisers
0.09% Sodium Azide (NaN3) 0.1% EACA 0.01% Benzamidine 1 mM EDTA
Storage Information
- Storage
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. - Guarantee
- Guaranteed until date of expiry. Please see product label.
More Information
- UniProt
- P07911
- Entrez Gene
- UMOD
- GO Terms
- GO:0005509 calcium ion binding
- GO:0005576 extracellular region
- GO:0006968 cellular defense response
- GO:0008285 negative regulation of cell proliferation
- GO:0031225 anchored to membrane
- GO:0016324 apical plasma membrane
- GO:0019898 extrinsic to membrane
- Regulatory
- For research purposes only
Applications of Tamm Horsfall Glycoprotein antibody
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA | 1/10,000 | 1/40,000 | |
Immunofluorescence | |||
Immunohistology - Frozen | 1/50 | 1/200 |
Secondary Antibodies Available
Description | Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|---|
Rabbit anti Sheep IgG (H/L):Biotin | 5184-2304 | C E F WB | 1.5 ml |
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Donkey anti Sheep/Goat IgG:DyLight®488 | STAR88D488GA | F IF | 0.1 mg |
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Donkey anti Sheep/Goat IgG:HRP | STAR88P | C E P WB | 1 ml |
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Product Specific References
References for Tamm Horsfall Glycoprotein antibody
-
El-Achkar, T.M. et al. (2011) Tamm-Horsfall protein-deficient thick ascending limbs promote injury to neighboring S3 segments in an MIP-2-dependent mechanism.
Am J Physiol Renal Physiol. 300 (4): F999-1007. -
Hao, S. et al. (2011) Differential regulation of NFAT5 by NKCC2 isoforms in medullary thick ascending limb (mTAL) cells.
Am J Physiol Renal Physiol. 300: F966-75. -
Vekaria, R.M. et al. (2006) Immunolocalization of ectonucleotidases along the rat nephron.
Am J Physiol Renal Physiol. 290 (2): F550-60. -
El-Achkar, T.M. et al. (2013) Tamm-Horsfall protein translocates to the basolateral domain of thick ascending limbs, interstitium, and circulation during recovery from acute kidney injury.
Am J Physiol Renal Physiol. 304 (8): F1066-75. -
El-Achkar, T.M. et al. (2008) Tamm-Horsfall protein protects the kidney from ischemic injury by decreasing inflammation and altering TLR4 expression.
Am J Physiol Renal Physiol. 295 (2): F534-44. -
Nevo, N. et al. (2010) Renal phenotype of the cystinosis mouse model is dependent upon genetic background.
Nephrol Dial Transplant. 25: 1059-66. -
Venables, G. et al. (2011) Ghrelin receptors are expressed by distal tubules of the mouse kidney.
Cell Tissue Res. 346: 135-9. -
Rice, J.C. et al. (2002) Monocyte chemoattractant protein-1 expression correlates with monocyte infiltration in the post-ischemic kidney.
Ren Fail. 24: 703-23. -
Liu, S. et al. (2012) Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury.
Autophagy. 8: 826-37. -
Saito, S. et al. (2011) Analysis of glial cell line-derived neurotrophic factor-inducible zinc finger protein 1 expression in human diseased kidney.
Hum Pathol. 42: 848-58. -
Ferrè, S. et al. (2014) Mutations in PCBD1 cause hypomagnesemia and renal magnesium wasting.
J Am Soc Nephrol. 25 (3): 574-86. -
Maeda-Hori, M. et al. (2014) Plasma CD147 reflects histological features in patients with lupus nephritis.
Lupus. 23: 342-52. -
Maruyama, H. et al. (2018) Medullary thick ascending limb impairment in the GlatmTg(CAG-A4GALT) Fabry model mice.
FASEB J. 32 (8): 4544-59. -
Choi, H.I. et al. (2019) Peroxiredoxin V (PrdxV) negatively regulates EGFR/Stat3-mediated fibrogenesis via a Cys48-dependent interaction between PrdxV and Stat3.
Sci Rep. 9 (1): 8751. -
Maydan, O. et al. (2018) Uromodulin deficiency alters tubular injury and interstitial inflammation but not fibrosis in experimental obstructive nephropathy.
Physiol Rep. 6 (6): e13654. -
Heitmeier, M. et al. (2014) The role of tumor necrosis factor alpha in regulating the expression of Tamm-Horsfall Protein (uromodulin) in thick ascending limbs during kidney injury.
Am J Nephrol. 40 (5): 458-67.
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