TAGLN antibody

Goat anti TAGLN

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
TAGLN

Product Code Applications Pack Size List Price Your Price Qty
VPA00048
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 100 µl
List Price Your Price
Search for Batch Specific Datasheets

Goat anti Human TAGLN antibody recognizes human TAGLN (transgelin), otherwise known as SM22-alpha. TAGLN is a shape change sensitive, actin cross-linking/gelling protein, and a member of the calponin family. TAGLN plays a role in calcium interactions and contractile properties of the cell.

TAGLN is ubiquitously expressed by vascular and visceral smooth muscle, is an early marker of smooth muscle differentiation and is overexpressed by senescent human fibroblasts. TAGLN is a tumor suppressor protein (Assinder et al. 2009), with markedly reduced expression in colorectal cancer samples, and may serve as an important biomarker of malignancy.

Goat anti Human TAGLN antibody recognizes TAGLN as a band of 22 kDa in a wide range of human cell line lysates. Cross reactivity with rodent cell lines is also observed.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Goat anti TAGLN detects a band of approximately 22 kDa in HeLa cell lysates.
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Goat polyclonal antibody purified by affinity chromatography.
Buffer Solution
TRIS buffered saline.
Preservative Stabilisers
0.02% Sodium Azide (NaN3)
0.5% Bovine Serum Albumin
Immunogen
Synthetic peptide sequence C-MTGYGRPRQIIS from the C-terminal region of TAGLN.
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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Description Donkey anti Sheep/Goat IgG:HRP

UniProt
Q01995
Entrez Gene
TAGLN
GO Terms
GO:0003779 actin binding
GO:0005737 cytoplasm
GO:0007517 muscle organ development
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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