Superoxide Dismutase (MN) antibody
Goat anti Human superoxide dismutase (Mn) antibody recognizes manganese superoxide dismutase (MNSOD) or SOD2, a superoxide dismutase with manganese at the active site. Superoxide dismutases (SOD) are a class of enzymes that catalyze the dismutation of superoxide into oxygen and hydrogen peroxide. As such, they are an important antioxidant defense in nearly all cells exposed to oxygen. There are three major families of superoxide dismutase, depending on the metal cofactor: Cu-Zn (which binds both copper and zinc), Fe and Mn types (which bind either iron or manganese), and finally the Ni type, which binds nickel.
Goat anti Human superoxide dismutase (Mn) antibody recognises human superoxide dismutase (Mn) as a single band of 24 kDa in range of human cell line lysates.
Goat anti Human superoxide dismutase (Mn) antibody recognises human superoxide dismutase (Mn) as a single band of 24 kDa in range of human cell line lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Goat anti superoxide dismutase (Mn) detects a band of approximately 24 kDa in K562 cell lysates.
- Product Form
- Purified IgG - liquid
- Preparation
- Goat polyclonal antibody purified by affinity chromatography
- Buffer Solution
- TRIS buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide (NaN3)
0.5% Bovine Serum Albumin - Immunogen
- Synthetic peptide with sequence C-EAIKRDFGSFDK from the internal region of the protein.
Storage Information
- Storage
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- Guarantee
- As supplied, 12 months from date of despatch.
More Information
- UniProt
- P04179
- Entrez Gene
- SOD2
- GO Terms
- GO:0005515 protein binding
- GO:0001315 age-dependent response to reactive oxygen species
- GO:0001836 release of cytochrome c from mitochondria
- GO:0003069 vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure
- GO:0004784 superoxide dismutase activity
- GO:0005759 mitochondrial matrix
- GO:0006357 regulation of transcription from RNA polymerase II promoter
- GO:0019430 removal of superoxide radicals
- GO:0030145 manganese ion binding
- GO:0032364 oxygen homeostasis
- GO:0043524 negative regulation of neuron apoptosis
- GO:0051289 protein homotetramerization
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- Regulatory
- For research purposes only
Applications of Superoxide Dismutase (MN) antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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