Superoxide Dismutase (MN) antibody

Goat anti Superoxide Dismutase (MN)

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
Superoxide Dismutase (MN)

Product Code Applications Pack Size List Price Your Price Qty
VPA00069
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 100 µl
List Price Your Price
Search for Batch Specific Datasheets

Goat anti Human superoxide dismutase (Mn) antibody recognizes manganese superoxide dismutase (MNSOD) or SOD2, a superoxide dismutase with manganese at the active site. Superoxide dismutases (SOD) are a class of enzymes that catalyze the dismutation of superoxide into oxygen and hydrogen peroxide. As such, they are an important antioxidant defense in nearly all cells exposed to oxygen. There are three major families of superoxide dismutase, depending on the metal cofactor: Cu-Zn (which binds both copper and zinc), Fe and Mn types (which bind either iron or manganese), and finally the Ni type, which binds nickel.

Goat anti Human superoxide dismutase (Mn) antibody recognises human superoxide dismutase (Mn) as a single band of 24 kDa in range of human cell line lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Goat anti superoxide dismutase (Mn) detects a band of approximately 24 kDa in K562 cell lysates.
Product Form
Purified IgG - liquid
Preparation
Goat polyclonal antibody purified by affinity chromatography.
Buffer Solution
TRIS buffered saline.
Preservative Stabilisers
0.02% Sodium Azide (NaN3)
0.5% Bovine Serum Albumin
Immunogen
Synthetic peptide with sequence C-EAIKRDFGSFDK from the internal region of the protein.
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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Synonyms
SOD2
UniProt
P04179
Entrez Gene
SOD2
GO Terms
GO:0005515 protein binding
GO:0001315 age-dependent response to reactive oxygen species
GO:0001836 release of cytochrome c from mitochondria
GO:0003069 vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure
GO:0004784 superoxide dismutase activity
GO:0005759 mitochondrial matrix
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0019430 removal of superoxide radicals
GO:0030145 manganese ion binding
GO:0032364 oxygen homeostasis
GO:0043524 negative regulation of neuron apoptosis
GO:0051289 protein homotetramerization