Superoxide Dismutase (MN) antibody

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Goat anti Superoxide Dismutase (MN)

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Product Code Applications Pack Size List Price Quantity
VPA00069
Datasheet
WB
MSDS
100 µl

Goat anti Human superoxide dismutase (Mn) antibody recognizes manganese superoxide dismutase (MNSOD) or SOD2, a superoxide dismutase with manganese at the active site. Superoxide dismutases (SOD) are a class of enzymes that catalyze the dismutation of superoxide into oxygen and hydrogen peroxide. As such, they are an important antioxidant defense in nearly all cells exposed to oxygen. There are three major families of superoxide dismutase, depending on the metal cofactor: Cu-Zn (which binds both copper and zinc), Fe and Mn types (which bind either iron or manganese), and finally the Ni type, which binds nickel.

Goat anti Human superoxide dismutase (Mn) antibody recognises human superoxide dismutase (Mn) as a single band of 24 kDa in range of human cell line lysates.

Product Details

Target Species
Human
Western Blotting
Goat anti superoxide dismutase (Mn) detects a band of approximately 24 kDa in K562 cell lysates.
Product Form
Purified IgG - liquid
Preparation
Goat polyclonal antibody purified by affinity chromatography
Buffer Solution
TRIS buffered saline
Preservative Stabilisers
0.02% Sodium Azide (NaN3)
0.5% Bovine Serum Albumin
Immunogen
Synthetic peptide with sequence C-EAIKRDFGSFDK from the internal region of the protein.

Storage Information

Storage
Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
Guarantee
As supplied, 12 months from date of despatch.

More Information

UniProt
P04179
Entrez Gene
SOD2
GO Terms
GO:0005515 protein binding
GO:0001315 age-dependent response to reactive oxygen species
GO:0001836 release of cytochrome c from mitochondria
GO:0003069 vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure
GO:0004784 superoxide dismutase activity
GO:0005759 mitochondrial matrix
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0019430 removal of superoxide radicals
GO:0030145 manganese ion binding
GO:0032364 oxygen homeostasis
GO:0043524 negative regulation of neuron apoptosis
GO:0051289 protein homotetramerization
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory
For research purposes only

Applications of Superoxide Dismutase (MN) antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Donkey anti Sheep/Goat IgG:HRP STAR88P C E P WB 1 ml loader