STK11 antibody

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Rabbit anti STK11

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Product Code Applications Pack Size List Price Quantity
AHP2733
Datasheet
WB
SDS
50 µl loader

Rabbit anti STK11 antibody recognizes serine/threonine-protein kinase STK11, also known as liver kinase B1, LKB1, hLKB1 and renal carcinoma antigen NY-REN-19. STK11 is a tumor suppressor and mutations in the STK11 gene are found in Peutz-Jeghers syndrome (PJS) (Marignani 2005). STK11 phosphorylates AMPK (Hardie 2004).

Product Details

Target Species
Human
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to STK11 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.02% Sodium Azide
50% Glycerol
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 134-433 of human STK11

Storage Information

Storage
Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Guarantee
12 months from date of despatch

More Information

UniProt
Q15831
Entrez Gene
STK11
GO Terms
GO:0000287 magnesium ion binding
GO:0005829 cytosol
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0006112 energy reserve metabolic process
GO:0006468 protein phosphorylation
GO:0007050 cell cycle arrest
GO:0008286 insulin receptor signaling pathway
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway
GO:0042304 regulation of fatty acid biosynthetic process
GO:0043276 anoikis
GO:0046320 regulation of fatty acid oxidation
Regulatory
For research purposes only

Applications of STK11 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/500 1/2000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
Rabbit anti STK11 antibody detects a band of approximately 54 kDa in U-87MG and SKOV3 cell lysates and mouse heart tissue lysate under reducing conditions

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Rabbit IgG (Fc):Biotin STAR121B E WB 1 mg loader
Goat anti Rabbit IgG (Fc):FITC STAR121F F 1 mg loader
Goat anti Rabbit IgG (Fc):HRP STAR121P E WB 1 mg loader
Goat anti Rabbit IgG (H/L):HRP STAR124P C E WB 1 mg loader
Sheep anti Rabbit IgG:FITC STAR34B C F 1 mg loader
Sheep anti Rabbit IgG:RPE STAR35A F 1 ml loader
Sheep anti Rabbit IgG:DyLight®488 STAR36D488GA F IF WB 0.1 mg
Sheep anti Rabbit IgG:DyLight®680 STAR36D680GA F IF WB 0.1 mg
Sheep anti Rabbit IgG:Dylight®800 STAR36D800GA F IF WB 0.1 mg