STIP1 antibody

Rabbit anti STIP1

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
STIP1

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VPA00202
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Rabbit anti Human STIP1 antibody recognizes the stress-induced-phosphoprotein 1 (STIP1), also known as Hsp70/Hsp90-organizing protein, NY-REN-11 antigen, epididymis secretory sperm binding protein Li 94n, hsc70/Hsp90-organizing protein, renal carcinoma antigen NY-REN-11 and transformation-sensitive protein IEF SSP 3521.

STIP1 is an adaptor protein that coordinates the functions of HSP70 and HSP90 in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 (PubMed 16100115) (supplied by OMIM, Jul 2009).

Rabbit anti Human STIP1 antibody detects a band of 64 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti STIP1 detects a band of approximately 64 kDa in Jurkat cell lysates.
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Rabbit Ig fraction prepared by ammonium sulphate precipitation.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3).
Immunogen
KLH conjugated synthetic peptide between 461-488 amino acids from the C-terminal region of human STIP1
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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UniProt
P31948
Entrez Gene
STIP1
GO Terms
GO:0005515 protein binding
GO:0005634 nucleus
GO:0005794 Golgi apparatus
GO:0006950 response to stress
GO:0007411 axon guidance
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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