STEAP1 antibody


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WB P ResetRabbit anti STEAP1 (C-Terminal)
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- STEAP1
- Region
- (C-TERMINAL)
Rabbit anti Human STEAP1 antibody recognizes STEAP1, also known as six transmembrane epithelial antigen of the prostate. STEAP1 is a ~39 kDa protein and member of a family of cell surface serpentine transmembrane antigens of the prostate. STEAP1 is predominantly expressed in human prostate and is up-regulated in several cancer lines including prostate, ovarian, cervical, breast, testicular, bladder, colon and Ewing sarcoma. It is significantly expressed at cell-cell junctions and has been shown to be a target of human CD8 T cells. This indicates that it could be used as a potential target for cancer immunotherapy. This antibody does not cross-react with other STEAP-proteins. |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Rat Mouse - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Antisera to human STEAP (CT) were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.02% Sodium Azide - Immunogen
- An 18 amino acid peptide located near the c-terminal region of human STEAP1.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Immunohistology - Paraffin 1 | ![]() |
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Western Blotting | ![]() |
1 | 2ug/ml |
- 1This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.
- Western Blotting
- AHP1438 detects a band of approximately 40kDa in human spleen cell lysates.
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
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Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg |
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Description | Goat anti Rabbit IgG (Fc):Biotin | ||||||
Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg |
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Description | Goat anti Rabbit IgG (Fc):FITC | ||||||
Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg |
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Description | Goat anti Rabbit IgG (Fc):HRP | ||||||
Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg |
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Description | Goat anti Rabbit IgG (H/L):HRP | ||||||
Sheep anti Rabbit IgG:FITC | STAR34B | C F | 1 mg |
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Description | Sheep anti Rabbit IgG:FITC | ||||||
Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
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Description | Sheep anti Rabbit IgG:RPE |
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Antigen Retrieval Buffer, pH8.0 | BUF025A | P | 500 ml | Log in | |||
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Description | Antigen Retrieval Buffer, pH8.0 | ||||||
TidyBlot Western Blot Detection Reagent:HRP | STAR209P | WB* | 0.5 ml | Log in | |||
List Price | Your Price | ||||||
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Description | TidyBlot Western Blot Detection Reagent:HRP |
Further Reading
-
Hubert, R.S. et al. (1999) STEAP: a prostate-specific cell-surface antigen highly expressed in human prostate tumors.
Proc Natl Acad Sci U S A. 96 (25): 14523-8. -
Alves, P.M. et al. (2006) STEAP, a prostate tumor antigen, is a target of human CD8+ T cells.
Cancer Immunol Immunother. 55 (12): 1515-23.
- Synonyms
- STEAP
- RRID
- AB_2271260
- UniProt
- Q9UHE8
- Entrez Gene
- STEAP1
- GO Terms
- GO:0009055 electron carrier activity
- GO:0005887 integral to plasma membrane
- GO:0005506 iron ion binding
- GO:0005911 cell-cell junction
- GO:0016491 oxidoreductase activity
- GO:0022900 electron transport chain
- GO:0006826 iron ion transport
- GO:0010008 endosome membrane
- GO:0015267 channel activity
- View More GO Terms
- GO:0050660 flavin adenine dinucleotide binding
AHP1438

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