STAT4 (pTyr693) antibody

Rabbit anti STAT4 (pTyr693)

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
STAT4 (pTyr693)

Product Code Applications Pack Size List Price Your Price Qty
AHP2687
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
P WB 50 µl loader
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Rabbit anti STAT4 (pTyr693) antibody recognizes STAT4 when phosphorylated at tyrosine 693. STAT4 is a member of the STAT4 family of transcription factors. STAT4 is phosphorylated at tyrosine 693 by JAKs leading to homodimerzation and translocation to the nucleus (Wurster et al. 2000).

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse Expected from Sequence
Rat Expected from Sequence
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to STAT4 (pTyr693) was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.02% Sodium Azide
50% Glycerol
Immunogen
Phospho specific-peptide corresponding to residues surrounding tyrosine 693 of human STAT4
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Paraffin 1/50 1/100
Western Blotting 1/500 1/2000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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Further Reading

  1. Wurster AL et al. (2000) The biology of Stat4 and Stat6.
    Oncogene. 19 (21): 2577-84.

UniProt
Q14765
Entrez Gene
STAT4
GO Terms
GO:0005515 protein binding
GO:0005509 calcium ion binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0004871 signal transducer activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-dependent
GO:0007259 JAK-STAT cascade
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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