STAT2 (pTyr690) antibody
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WB ResetRabbit anti STAT2 (pTyr690)
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- STAT2 (pTyr690)
Antibody Quality and Performance Guarantee
| Rabbit anti STAT2 (pTyr690) antibody recognizes STAT2, also known as p113 when phosphorylated at tyrosine 690. STAT2 is a member of the STAT family of transcription factors. Upon ligand binding receptor associated kinases phosphorylate STATs causing them to dimerize and translocate to the nucleus. STAT2 forms a heterodimer with STAT1 where promotes transcription at interferon-sensitive response elements. Phosphorylation of STAT2 at tyrosine 690 by JAKs promotes the dimerization with STAT1. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to STAT2 (pTyr690) was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.05% Proclin™300
50% Glycerol - Immunogen
- Phospho specific-peptide corresponding to residues surrounding tyrosine 690 of human STAT2
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
- Acknowledgements
- ProClin™ is a trademark of The Dow Chemical Company (“Dow”) or an affiliated company of Dow.
Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/500 | 1/1000 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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- UniProt
- P52630
- Entrez Gene
- STAT2
- GO Terms
- GO:0005886 plasma membrane
- GO:0005515 protein binding
- GO:0005509 calcium ion binding
- GO:0003677 DNA binding
- GO:0003700 sequence-specific DNA binding transcription factor activity
- GO:0009615 response to virus
- GO:0005829 cytosol
- GO:0004871 signal transducer activity
- GO:0005654 nucleoplasm
- View More GO Terms
- GO:0006357 regulation of transcription from RNA polymerase II promoter
- GO:0007259 JAK-STAT cascade
- GO:0044419 interspecies interaction between organisms
- GO:0060337 type I interferon-mediated signaling pathway
- GO:0060338 regulation of type I interferon-mediated signaling pathway
View more products with STAT2 specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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