SMARCC1 antibody

Rabbit anti SMARCC1

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
SMARCC1

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VPA00337
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Rabbit anti Human SMARCC1 antibody recognizes SMARCC1, also known as BRG1-associated factor 155, SWI/SNF complex 155 kDa subunit, SWI/SNF complex subunit SMARCC1, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1, chromatin remodeling complex BAF155 subunit and mammalian chromatin remodeling complex BRG1-associated factor 155.

The protein encoded by the SMARCC1 gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors (provided by RefSeq, Jul 2008).

Rabbit anti Human SMARCC1 antibody detects a band of 161 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti SMARCC1 detects a band of approximately 161 kDa in NIH/3T3 cell lysate.
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography on Protein A.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
2% Sucrose
Immunogen
Synthetic peptide corresponding to the C-terminal region of human SMARCC1
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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UniProt
Q92922
Entrez Gene
SMARCC1
GO Terms
GO:0003677 DNA binding
GO:0003713 transcription coactivator activity
GO:0006333 chromatin assembly or disassembly
GO:0005654 nucleoplasm
GO:0006338 chromatin remodeling
GO:0007399 nervous system development
GO:0016514 SWI/SNF complex
GO:0047485 protein N-terminus binding
GO:0071564 npBAF complex
GO:0071565 nBAF complex
GO:0071778 WINAC complex
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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