SMAD4 antibody
Filter by Application:
WB ResetRabbit anti SMAD4
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- SMAD4
Antibody Quality and Performance Guarantee
| Rabbit anti SMAD4 antibody recognizes SMAD4, also known as mothers against decapentaplegic homolog 4 and deletion target in pancreatic carcinoma 4. SMAD4 is a transcription factor and belongs to the dwarfin/SMAD family. SMAD4 is categorized as the common mediator SMAD (co-SMAD); it associates with receptor-regulated SMADS (SMAD1, SMAD2, SMAD3, SMAD5 and SMAD8) and plays a key role in the TGF-beta signaling pathway. |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Expected from Sequence Rat Expected from Sequence - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to SMAD4 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide
50% Glycerol - Immunogen
- Recombinant human SMAD4
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/500 | 1/2000 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti SMAD4 antibody detects a band of approximately 60 kDa in cell lysates under reducing conditions
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg |
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| Description | Goat anti Rabbit IgG (Fc):Biotin | ||||||
| Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg |
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| Description | Goat anti Rabbit IgG (Fc):FITC | ||||||
| Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg |
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| Description | Goat anti Rabbit IgG (Fc):HRP | ||||||
| Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg |
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| Description | Goat anti Rabbit IgG (H/L):HRP | ||||||
| Sheep anti Rabbit IgG:FITC | STAR34B | C F | 1 mg |
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| Description | Sheep anti Rabbit IgG:FITC | ||||||
| Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
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| Description | Sheep anti Rabbit IgG:RPE | ||||||
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| TidyBlot Western Blot Detection Reagent:HRP | STAR209P | WB* | 0.5 ml | Log in | |||
| List Price | Your Price | ||||||
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| Description | TidyBlot Western Blot Detection Reagent:HRP | ||||||
- UniProt
- Q13485
- Entrez Gene
- SMAD4
- GO Terms
- GO:0001666 response to hypoxia
- GO:0003700 sequence-specific DNA binding transcription factor activity
- GO:0005829 cytosol
- GO:0030616 transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
- GO:0005813 centrosome
- GO:0007179 transforming growth factor beta receptor signaling pathway
- GO:0007183 SMAD protein complex assembly
- GO:0010718 positive regulation of epithelial to mesenchymal transition
- GO:0010843 promoter binding
- View More GO Terms
- GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
- GO:0030308 negative regulation of cell growth
- GO:0030509 BMP signaling pathway
- GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway
- GO:0032444 activin responsive factor complex
- GO:0032909 regulation of transforming growth factor-beta2 production
- GO:0042177 negative regulation of protein catabolic process
- GO:0042803 protein homodimerization activity
- GO:0045892 negative regulation of transcription, DNA-dependent
- GO:0060021 palate development
- GO:0060391 positive regulation of SMAD protein import into nucleus
- GO:0060395 SMAD protein signal transduction
- GO:0070411 I-SMAD binding
- GO:0070412 R-SMAD binding
AHP2521
141485
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