SKAP2 antibody
Rabbit anti Human SKAP2 antibody recognizes SKAP2, also known as SCAP2, Fyn-associated phosphoprotein SKAP55 homologue, Pyk2/RAFTK-associated protein, retinoic acid-induced protein 70 and src family associated phosphoprotein 2.
The protein encoded by the SKAP2 gene belongs to the src family kinases. This protein is similar to the src kinase associated phosphoprotein 1. It is an adaptor protein that is thought to play an essential role in the src signaling pathway in various cells. It inhibits PTK2B/RAFTK activity and regulates alpha-synuclein phosphorylation. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly (provided by RefSeq, Jul 2008).
Rabbit anti Human SKAP2 antibody detects a band of 45 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
The protein encoded by the SKAP2 gene belongs to the src family kinases. This protein is similar to the src kinase associated phosphoprotein 1. It is an adaptor protein that is thought to play an essential role in the src signaling pathway in various cells. It inhibits PTK2B/RAFTK activity and regulates alpha-synuclein phosphorylation. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly (provided by RefSeq, Jul 2008).
Rabbit anti Human SKAP2 antibody detects a band of 45 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Anti SKAP2 detects a band of approximately 45 kDa in HeLa cell lysate
- Product Form
- Purified IgG - liquid
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
2% Sucrose - Immunogen
- Synthetic peptide corresponding to the central region of Human SKAP2
Storage Information
- Storage
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- O75563
- Entrez Gene
- SKAP2
- GO Terms
- GO:0005886 plasma membrane
- GO:0005829 cytosol
- GO:0007165 signal transduction
- GO:0005070 SH3/SH2 adaptor activity
- GO:0006461 protein complex assembly
- GO:0034329 cell junction assembly
- GO:0042113 B cell activation
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
- Regulatory
- For research purposes only
Applications of SKAP2 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Rabbit IgG (H/L):HRP | STAR208P | WB | 2 ml |
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