SAM68 antibody
Rabbit anti Human SAM68 antibody recognizes the KH domain-containing, RNA-binding, signal transduction-associated protein 1, also known as GAP-associated tyrosine phosphoprotein p62 (Sam68), p21 Ras GTPase-activating protein-associated p62 or src-associated in mitosis 68 kDa protein.
The KHDRBS1 gene encodes a member of the K homology domain-containing, RNA-binding, signal transduction-associated protein family. The encoded protein appears to have many functions and may be involved in a variety of cellular processes, including alternative splicing, cell cycle regulation, RNA 3'-end formation, tumorigenesis, and regulation of human immunodeficiency virus gene expression. Alternative splicing results in multiple transcript variants (provided by RefSeq, Dec 2012).
Rabbit anti Human SAM68 antibody detects a band of 68 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
The KHDRBS1 gene encodes a member of the K homology domain-containing, RNA-binding, signal transduction-associated protein family. The encoded protein appears to have many functions and may be involved in a variety of cellular processes, including alternative splicing, cell cycle regulation, RNA 3'-end formation, tumorigenesis, and regulation of human immunodeficiency virus gene expression. Alternative splicing results in multiple transcript variants (provided by RefSeq, Dec 2012).
Rabbit anti Human SAM68 antibody detects a band of 68 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Rabbit anti SAM68 detects a band of approximately 68 kDa in K562 cell lysates
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
2% Sucrose - Immunogen
- Synthetic peptide encompassing part of the middle region of human SAM68
Storage Information
- Storage
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- Q07666
- Entrez Gene
- KHDRBS1
- GO Terms
- GO:0000086 G2/M transition of mitotic cell cycle
- GO:0003677 DNA binding
- GO:0003723 RNA binding
- GO:0016020 membrane
- GO:0005070 SH3/SH2 adaptor activity
- GO:0005634 nucleus
- GO:0006350 transcription
- GO:0006397 mRNA processing
- GO:0007050 cell cycle arrest
- GO:0007166 cell surface receptor linked signaling pathway
- GO:0008283 cell proliferation
- GO:0016564 transcription repressor activity
- GO:0017124 SH3 domain binding
- GO:0046831 regulation of RNA export from nucleus
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
- Regulatory
- For research purposes only
Applications of SAM68 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Rabbit IgG (H/L):HRP | STAR208P | WB | 2 ml |
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