SAM68 antibody

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Rabbit anti SAM68

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Product Code Applications Pack Size List Price Quantity
VPA00611
Datasheet
WB
MSDS
100 µl loader

Rabbit anti Human SAM68 antibody recognizes the KH domain-containing, RNA-binding, signal transduction-associated protein 1, also known as GAP-associated tyrosine phosphoprotein p62 (Sam68), p21 Ras GTPase-activating protein-associated p62 or src-associated in mitosis 68 kDa protein.

The KHDRBS1 gene encodes a member of the K homology domain-containing, RNA-binding, signal transduction-associated protein family. The encoded protein appears to have many functions and may be involved in a variety of cellular processes, including alternative splicing, cell cycle regulation, RNA 3'-end formation, tumorigenesis, and regulation of human immunodeficiency virus gene expression. Alternative splicing results in multiple transcript variants (provided by RefSeq, Dec 2012).

Rabbit anti Human SAM68 antibody detects a band of 68 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species
Human
Western Blotting
Rabbit anti SAM68 detects a band of approximately 68 kDa in K562 cell lysates
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide
2% Sucrose
Immunogen
Synthetic peptide encompassing part of the middle region of human SAM68

Storage Information

Storage
Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
Guarantee
As supplied, 12 months from date of despatch.

More Information

UniProt
Q07666 Related reagents
Entrez Gene
KHDRBS1 Related reagents
GO Terms
GO:0000086 G2/M transition of mitotic cell cycle
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0016020 membrane
GO:0005070 SH3/SH2 adaptor activity
GO:0005634 nucleus
GO:0006350 transcription
GO:0006397 mRNA processing
GO:0007050 cell cycle arrest
GO:0007166 cell surface receptor linked signaling pathway
GO:0008283 cell proliferation
GO:0016564 transcription repressor activity
GO:0017124 SH3 domain binding
GO:0046831 regulation of RNA export from nucleus
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories
Regulatory
For research purposes only

Applications of SAM68 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Rabbit IgG (H/L):HRP STAR208P WB 2 ml

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