S-ADENOSYLHOMOCYSTEINE Hydrolase antibody
Rabbit anti Human S-adenosylhomocysteine hydrolase antibody recognizes S-adenosylhomocysteine hydrolase, also known as DC-expressed AHCY-like molecule, S-adenosyl-L-homocysteine hydrolase, IP(3)Rs binding protein released with IP(3), IRBIT or S-adenosylhomocysteine hydrolase-like protein 1.
S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for AHCY (provided by RefSeq, Jun 2009).
Rabbit anti Human S-adenosylhomocysteine hydrolase antibody detects a band of 47 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for AHCY (provided by RefSeq, Jun 2009).
Rabbit anti Human S-adenosylhomocysteine hydrolase antibody detects a band of 47 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Anti S-adenosylhomocysteine hydrolase detects a band of approximately 47 kDa in HEK293 cell lysates.
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Ig fraction - liquid.
- Preparation
- Rabbit Ig fraction prepared by ammonium sulphate precipitation.
- Buffer Solution
- Phosphate buffered saline.
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3).
- Immunogen
- KLH conjugated synthetic peptide corresponding to amino acid 407-432 of human S-adenosylhomocysteine hydrolase.
Storage Information
- Storage
- Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P23526
- Entrez Gene
- AHCY
- GO Terms
- GO:0005515 protein binding
- GO:0004013 adenosylhomocysteinase activity
- GO:0005829 cytosol
- GO:0006805 xenobiotic metabolic process
- GO:0032259 methylation
- GO:0042470 melanosome
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
- Regulatory
- For research purposes only.
Applications of S-ADENOSYLHOMOCYSTEINE Hydrolase antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Rabbit IgG (H/L):HRP | STAR208P | WB | 2 ml |
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