RPS19 antibody

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Rabbit anti RPS19

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Product Code Applications Pack Size List Price Quantity
VPA00508
Datasheet
WB
MSDS
100 µl loader

Rabbit anti Human RPS19 antibody recognizes RPS19, also known as 40S ribosomal protein S19.

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPS19 gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in RPS19 cause Diamond-Blackfan anemia 1 (DBA1), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for RPS19 in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of RPS19 in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of RPS19 dispersed through the genome (provided by RefSeq, Jul 2008).

Rabbit anti Human RPS19 antibody detects a band of 18 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species
Human
Western Blotting
Anti RPS19 detects a band of approximately 18 kDa in HeLa cell lysates.
Product Form
Purified IgG - liquid.
Preparation
Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
2% Sucrose.
Immunogen
Synthetic peptide directed towards the C-terminal region of human RPS19

Storage Information

Storage
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
Guarantee
12 months from date of despatch

More Information

UniProt
P39019
Entrez Gene
RPS19
GO Terms
GO:0022627 cytosolic small ribosomal subunit
GO:0005515 protein binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005730 nucleolus
GO:0006364 rRNA processing
GO:0006414 translational elongation
GO:0006415 translational termination
GO:0009991 response to extracellular stimulus
GO:0015669 gas transport
GO:0019083 viral transcription
GO:0030218 erythrocyte differentiation
GO:0031018 endocrine pancreas development
GO:0042274 ribosomal small subunit biogenesis
GO:0051272 positive regulation of cellular component movement
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories
Regulatory
For research purposes only.

Applications of RPS19 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Rabbit IgG (H/L):HRP STAR208P WB 2 ml