RPL17 antibody

Rabbit anti RPL17

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
RPL17

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VPA00363
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Rabbit anti Human RPL17 antibody recognizes RPL17, also known as 60S ribosomal protein L17, 60S ribosomal protein L23 or gene encoding putative NFkB activating protein.

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. The RPL17 gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22P family of ribosomal proteins. It is located in the cytoplasm. RPL17 has been referred to as rpL23 because the encoded protein shares amino acid identity with ribosomal protein L23 from Halobacterium marismortui; however, its official symbol is RPL17. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of RPL17 dispersed through the genome. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between RPL17 and the neighboring downstream C18orf32 (chromosome 18 open reading frame 32) gene (provided by RefSeq, Dec 2010).

Rabbit anti Human RPL17 antibody detects bands of 22 and 24 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti RPL17 detects a bands of approximately 22 and 24 kDa in HeLa cell lysate.
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3).
Immunogen
KLH-conjugated synthetic peptide corresponding to aa 156-184 of human RPL17
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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UniProt
P18621
Entrez Gene
RPL17
GO Terms
GO:0003735 structural constituent of ribosome
GO:0005829 cytosol
GO:0006414 translational elongation
GO:0006415 translational termination
GO:0015934 large ribosomal subunit
GO:0019083 viral transcription
GO:0031018 endocrine pancreas development
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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