RPAP3 antibody

ISO 9001 Quality Assurance Manufacturing | Print

Anti RPAP3 Antibody gallery image 1 — Western blot analysis was performed by loading 25µg of various whole cell lysates probed with Rabbit anti RPAP3 (**AHP2999**) at 1/1000 dilution. Arrow points to RPAP3 (molecular weight 76 kDa).

Rabbit anti RPAP3

Product Type: Polyclonal Antibody
Isotype: Polyclonal IgG
Specificity: RPAP3

Quick Links:

Secondary Antibodies
Applications
Storage Information
Batch/Lot Specific Datasheets

Antibody Quality and Performance Guarantee

Unrivaled Technical Support

Product Code Applications Pack Size List Price Your Price Qty

List Price	Your Price
AHP2999 Datasheet Datasheet SDS SDS	WB	50 µl		Log in	Get Quote
	Log in

Rabbit anti RPAP3 antibody recognizes RNA polymerase II-associated protein 3 (RPAP3), also known as HSpagh and Tah1.

It is a component of the R2TP/PFDL complex (Cloutier et al. 2009) and provides a flexible scaffold for allowing the abundant molecular chaperone HSP90 to interact with other proteins including RNA Pol II, TOR and SMG1, allowing the assembly of important cellular complexes (Martino et al. 2018). It has been suggested that RPAP3 can modulate UV-induced DNA damage (Ni et al. 2009). RPAP3 appears to bind to NEMO, inhibiting the NF-kappaB signaling pathway and enhancing cytotoxicity of the chemotherapeutic agent doxorubicin (Shimada et al. 2011).

Target Species: Human
Species Cross-Reactivity: Target Species Cross Reactivity

Rat; N.B. Antibody reactivity and working conditions may vary between species.
Product Form: Purified IgG - liquid
Antiserum Preparation: Antiserum to RPAP3 was raised by repeated immunization of rabbits with highly purified antigen
Buffer Solution: Phosphate buffered saline
Preservative Stabilisers: 0.02% Sodium Azide
50% Glycerol
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 17-241 of human RPAP3 (NP_001139547)
Regulatory: For research purposes only
Guarantee: 12 months from date of despatch

Target Species	Cross Reactivity
Rat

Store at -20^oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/500	1/2000

Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

Description	Product Code	Applications	Pack Size	Your Price
Goat anti Rabbit IgG (Fc):Biotin	STAR121B	E WB	1 mg	Log in	Get Quote
List Price	Your Price
	Log in
Description	Goat anti Rabbit IgG (Fc):Biotin
Goat anti Rabbit IgG (Fc):FITC	STAR121F	F	1 mg	Log in	Get Quote
List Price	Your Price
	Log in
Description	Goat anti Rabbit IgG (Fc):FITC
Goat anti Rabbit IgG (Fc):HRP	STAR121P	E WB	1 mg	Log in	Get Quote
List Price	Your Price
	Log in
Description	Goat anti Rabbit IgG (Fc):HRP
Goat anti Rabbit IgG (H/L):HRP	STAR124P	C E WB	1 mg	Log in	Get Quote
List Price	Your Price
	Log in
Description	Goat anti Rabbit IgG (H/L):HRP
Sheep anti Rabbit IgG:FITC	STAR34B	C F	1 mg	Log in	Get Quote
List Price	Your Price
	Log in
Description	Sheep anti Rabbit IgG:FITC
Sheep anti Rabbit IgG:RPE	STAR35A	F	1 ml	Log in	Get Quote
List Price	Your Price
	Log in
Description	Sheep anti Rabbit IgG:RPE