RIP2 antibody

Rabbit anti RIP2

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
RIP2

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AHP2519
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SDS Safety Datasheet SDS
P WB 50 µl loader
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Rabbit anti RIP2 antibody recognizes receptor-interacting serine/threonine-protein kinase 2 (RIP2) also known as CARD-containing interleukin-1 beta-converting enzyme-associated kinase. RIP2 belongs to the serine/threonine protein kinase family and contributes to the regulation of the innate and adaptive immune system.

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to RIP2 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.02% Sodium Azide
50% Glycerol
Immunogen
Recombinant human RIP2
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Paraffin 1/50 1/200
Western Blotting 1/500 1/2000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
Rabbit anti RIP2 antibody detects a band of approximately 61 kDa in cell lysates and tissue lysates under reducing conditions

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UniProt
O43353
Entrez Gene
RIPK2
GO Terms
GO:0000187 activation of MAPK activity
GO:0002755 MyD88-dependent toll-like receptor signaling pathway
GO:0002756 MyD88-independent toll-like receptor signaling pathway
GO:0006915 apoptosis
GO:0005829 cytosol
GO:0004674 protein serine/threonine kinase activity
GO:0004871 signal transducer activity
GO:0005524 ATP binding
GO:0006916 anti-apoptosis
GO:0006954 inflammatory response
GO:0007254 JNK cascade
GO:0008063 Toll signaling pathway
GO:0030274 LIM domain binding
GO:0031398 positive regulation of protein ubiquitination
GO:0034130 toll-like receptor 1 signaling pathway
GO:0034134 toll-like receptor 2 signaling pathway
GO:0034138 toll-like receptor 3 signaling pathway
GO:0034142 toll-like receptor 4 signaling pathway
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0045087 innate immune response
GO:0048011 nerve growth factor receptor signaling pathway
GO:0050700 CARD domain binding
GO:0050852 T cell receptor signaling pathway
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051403 stress-activated MAPK cascade
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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