REG1A antibody
Rabbit anti Human REG1A antibody recognizes REG1A also known as Lithostathine-1-alpha, REG-1-alpha, islet cells regeneration factor, pancreatic thread protein, protein-X, regenerating islet-derived protein 1-alpha or regenerating protein I alpha.
REG1A is a type I subclass member of the Reg gene family, a multigene family grouped into four subclasses, types I, II, III and IV, based on the primary structures of the encoded proteins. REG1A encodes a protein that is secreted by the exocrine pancreas. It is associated with islet cell regeneration and diabetogenesis and may be involved in pancreatic lithogenesis. Reg family members REG1B, REGL, PAP and REG1A are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication (provided by RefSeq, Jul 2008).
Rabbit anti Human REG1A antibody detects a band of 14 kDa. The antibody has been extensively validated for western blotting using tissue and whole cell lysates.
REG1A is a type I subclass member of the Reg gene family, a multigene family grouped into four subclasses, types I, II, III and IV, based on the primary structures of the encoded proteins. REG1A encodes a protein that is secreted by the exocrine pancreas. It is associated with islet cell regeneration and diabetogenesis and may be involved in pancreatic lithogenesis. Reg family members REG1B, REGL, PAP and REG1A are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication (provided by RefSeq, Jul 2008).
Rabbit anti Human REG1A antibody detects a band of 14 kDa. The antibody has been extensively validated for western blotting using tissue and whole cell lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Anti REG1A detects a band of approximately 14 kDa in human pancreas tissue samples.
- Product Form
- Purified IgG - liquid.
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline.
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
2% Sucrose. - Immunogen
- Synthetic peptide directed towards the C-terminal region of human REG1A
Storage Information
- Storage
- Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P05451
- Entrez Gene
- REG1A
- GO Terms
- GO:0005576 extracellular region
- GO:0005529 sugar binding
- GO:0008083 growth factor activity
- GO:0008284 positive regulation of cell proliferation
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
- Regulatory
- For research purposes only.
Applications of REG1A antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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