RAP1A/B antibody

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Anti RAP1A/B Antibody (PrecisionAb Polyclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with RAP1A/B antibody followed by detection with HRP conjugated Goat anti Rabbit IgG antibody (1/10,000, STAR208P) and visualized on the ChemiDoc MP with 5 second exposure. Arrow points to RAP1A/B (molecular weight 26 kDa).

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Rabbit anti RAP1A/B

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified
Specificity: RAP1A/B

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VPA00481 Datasheet Datasheet SDS SDS	WB	100 µl		Log in	Get Quote
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Rabbit anti Human RAP1A / RAP1B antibody recognizes the Ras-related protein Rap-1a and Ras-related protein Rap-1b, also known as GTP-binding protein smg p21B, RAS-related protein RAP1B, Ras family small GTP binding protein RAP1B, small GTP binding protein.

RAP1A/RAP1B encodes members of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. The RAP1A protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. The RAP1B protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. RAP1B also plays a role in regulating outside-in signaling in platelets. Alternate splicing of RAP1A and RAP1B have been known to produce multiple transcript variants. Pseudogenes of RAP1A have been defined on chromosomes 14 and 17 (provided by RefSeq, May 2014). Pseudogenes of RAP1B are found on chromosomes 3, 5, 6 and 9. (provided by RefSeq, Oct 2011).

Rabbit anti Human RAP1A/ RAP1B antibody detects a band of 26 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Target Species: Human
Western Blotting: Anti RAP1A/B detects a band of approximately 26 kDa in HEK293 cell lysates.
Species Cross-Reactivity: Target Species Cross Reactivity

Mouse; N.B. Antibody reactivity and working conditions may vary between species.
Product Form: Purified IgG - liquid.
Preparation: Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution: Phosphate buffered saline.
Preservative Stabilisers: 0.09% Sodium Azide (NaN₃)
2% Sucrose.
Immunogen: Synthetic peptide directed towards the N terminal region of human RAP1B
Regulatory: For research purposes only.
Guarantee: 12 months from date of despatch.
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Target Species	Cross Reactivity
Mouse

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description	Product Code	Applications	Pack Size	Your Price
Goat anti Rabbit IgG (H/L):HRP	STAR208P	WB	2 ml	Log in	Get Quote
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Description	Goat anti Rabbit IgG (H/L):HRP

UniProt: P61224
Entrez Gene: RAP1B
GO Terms: GO:0005886 plasma membrane; GO:0005515 protein binding; GO:0003924 GTPase activity; GO:0007596 blood coagulation; GO:0005829 cytosol; GO:0005525 GTP binding; GO:0006112 energy reserve metabolic process; GO:0050796 regulation of insulin secretion; GO:0019003 GDP binding; View More GO Terms