RAP1A/B antibody

Rabbit anti RAP1A/B

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
RAP1A/B

Product Code Applications Pack Size List Price Your Price Qty
VPA00481
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 100 µl loader
List Price Your Price
loader

Rabbit anti Human RAP1A / RAP1B antibody recognizes the Ras-related protein Rap-1a and Ras-related protein Rap-1b, also known as GTP-binding protein smg p21B, RAS-related protein RAP1B, Ras family small GTP binding protein RAP1B, small GTP binding protein.

RAP1A/RAP1B encodes members of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. The RAP1A protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. The RAP1B protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. RAP1B also plays a role in regulating outside-in signaling in platelets. Alternate splicing of RAP1A and RAP1B have been known to produce multiple transcript variants. Pseudogenes of RAP1A have been defined on chromosomes 14 and 17 (provided by RefSeq, May 2014). Pseudogenes of RAP1B are found on chromosomes 3, 5, 6 and 9. (provided by RefSeq, Oct 2011).

Rabbit anti Human RAP1A/ RAP1B antibody detects a band of 26 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti RAP1A/B detects a band of approximately 26 kDa in HEK293 cell lysates.
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid.
Preparation
Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
2% Sucrose.
Immunogen
Synthetic peptide directed towards the N terminal region of human RAP1B
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description Product Code Applications Pack Size List Price Your Price Quantity
Goat anti Rabbit IgG (H/L):HRP STAR208P WB 2 ml
List Price Your Price
Description Goat anti Rabbit IgG (H/L):HRP

UniProt
P61224
Entrez Gene
RAP1B
GO Terms
GO:0005886 plasma membrane
GO:0005515 protein binding
GO:0003924 GTPase activity
GO:0007596 blood coagulation
GO:0005829 cytosol
GO:0005525 GTP binding
GO:0006112 energy reserve metabolic process
GO:0050796 regulation of insulin secretion
GO:0019003 GDP binding

VPA00481

160712

If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.

View more products with RAP1A/B specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Human Products