RAP1 antibody
Rabbit anti Human RAP1 antibody recognizes RAP1, also known as RAP1 homolog, TERF2-interacting telomeric protein 1, TRF2-interacting telomeric RAP1 protein, dopamine receptor interacting protein 5, hRap1, telomeric repeat binding factor 2 interacting protein and repressor/activator protein 1 homolog.
The RAP1 gene encodes a protein that is part of a complex involved in telomere length regulation. Pseudogenes are present on chromosomes 5 and 22 (provided by RefSeq, Apr 2010).
Rabbit anti Human RAP1 antibody detects a band of 50 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
The RAP1 gene encodes a protein that is part of a complex involved in telomere length regulation. Pseudogenes are present on chromosomes 5 and 22 (provided by RefSeq, Apr 2010).
Rabbit anti Human RAP1 antibody detects a band of 50 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Anti RAP1 detects a band of approximately 50 kDa in HeLa cell lysate
- Product Form
- Purified IgG - liquid
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- KLH-conjugated synthetic peptide corresponding to aa 349-378 of human RAP1
Storage Information
- Storage
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- Q9NYB0
- Entrez Gene
- TERF2IP
- GO Terms
- GO:0005515 protein binding
- GO:0000783 nuclear telomere cap complex
- GO:0003677 DNA binding
- GO:0005737 cytoplasm
- GO:0005654 nucleoplasm
- GO:0006350 transcription
- GO:0007004 telomere maintenance via telomerase
- GO:0010569 regulation of double-strand break repair via homologous recombination
- GO:0030870 Mre11 complex
- GO:0031848 protection from non-homologous end joining at telomere
- GO:0032205 negative regulation of telomere maintenance
- GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade
- GO:0048239 negative regulation of DNA recombination at telomere
- GO:0051092 positive regulation of NF-kappaB transcription factor activity
- GO:0070198 protein localization to chromosome, telomeric region
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- Regulatory
- For research purposes only
Applications of RAP1 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Rabbit IgG (H/L):HRP | STAR208P | WB | 2 ml |
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