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RAP1 antibody

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Western Blot Validated
Anti RAP1 Antibody (PrecisionAb Polyclonal Antibody) gallery image 1
Western blot analysis of whole cell lysates probed with RAP1 antibody followed by detection with HRP conjugated Goat anti Rabbit (1/10,000, STAR208P) and visualized on the ChemiDoc MP with 64 second exposure. Arrow points to RAP1 (molecular weight 50 kDa)

Rabbit anti RAP1

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
PrecisionAb Antibodies
Product Code Applications Pack Size List Price Quantity
VPA00341
Datasheet
WB
MSDS
100 µl loader

Rabbit anti Human RAP1 antibody recognizes RAP1, also known as RAP1 homolog, TERF2-interacting telomeric protein 1, TRF2-interacting telomeric RAP1 protein, dopamine receptor interacting protein 5, hRap1, telomeric repeat binding factor 2 interacting protein and repressor/activator protein 1 homolog.

The RAP1 gene encodes a protein that is part of a complex involved in telomere length regulation. Pseudogenes are present on chromosomes 5 and 22 (provided by RefSeq, Apr 2010).

Rabbit anti Human RAP1 antibody detects a band of 50 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species
Human
Western Blotting
Anti RAP1 detects a band of approximately 50 kDa in HeLa cell lysate
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
KLH-conjugated synthetic peptide corresponding to aa 349-378 of human RAP1

Storage Information

Storage
Store undiluted at -20oC, avoiding repeated freeze thaw cycles
Guarantee
12 months from date of despatch

More Information

UniProt
Q9NYB0
Entrez Gene
TERF2IP
GO Terms
GO:0005515 protein binding
GO:0000783 nuclear telomere cap complex
GO:0003677 DNA binding
GO:0005737 cytoplasm
GO:0005654 nucleoplasm
GO:0006350 transcription
GO:0007004 telomere maintenance via telomerase
GO:0010569 regulation of double-strand break repair via homologous recombination
GO:0030870 Mre11 complex
GO:0031848 protection from non-homologous end joining at telomere
GO:0032205 negative regulation of telomere maintenance
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0048239 negative regulation of DNA recombination at telomere
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0070198 protein localization to chromosome, telomeric region
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory
For research purposes only

Applications of RAP1 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Rabbit IgG (H/L):HRP STAR208P WB 2 ml

A Precise Solution to Reproducible Western Blots - PrecisionAb Antibodies
Request a different product with the RAP1 specificity