RANGAP1 antibody

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Rabbit anti RANGAP1

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Product Code Applications Pack Size List Price Quantity
VPA00866
Datasheet
WB
MSDS
100 µl loader

Rabbit anti Human RANGAP1 antibody recognizes the Ran GTPase-activating protein 1, also known as segregation distorter homolog.

RANGAP1 encodes a protein that associates with the nuclear pore complex and participates in the regulation of nuclear transport. The encoded protein interacts with Ras-related nuclear protein 1 (RAN) and regulates guanosine triphosphate (GTP)-binding and exchange. Alternative splicing results in multiple transcript variants (provided by RefSeq, Jul 2013).

Rabbit anti Human RANGAP1 antibody detects bands of 68 and 82 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species
Human
Western Blotting
Anti RANGAP1 antibody recognizes bands of approximately 68 & 82 kDa in MCF7 cell lysates
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography on immunogen
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide
2% Sucrose
Immunogen
Synthetic peptide corresponding to the middle region of human RANGAP1

Storage Information

Storage
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
Guarantee
12 months from date of despatch

More Information

UniProt
P46060
Entrez Gene
RANGAP1
GO Terms
GO:0005515 protein binding
GO:0000236 mitotic prometaphase
GO:0000777 condensed chromosome kinetochore
GO:0000922 spindle pole
GO:0005829 cytosol
GO:0007165 signal transduction
GO:0005098 Ran GTPase activator activity
GO:0005625 soluble fraction
GO:0005643 nuclear pore
GO:0031965 nuclear membrane
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories
Regulatory
For research purposes only

Applications of RANGAP1 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Rabbit IgG (H/L):HRP STAR208P WB 2 ml