Proto-Oncogene c-Rel antibody

Rabbit anti Proto-Oncogene c-Rel

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
Proto-Oncogene c-Rel

Product Code Applications Pack Size List Price Your Price Qty
VPA00227
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 100 µl loader
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Rabbit anti Human proto-oncogene c-Rel antibody recognizes proto-oncogene c-Rel, also known as oncogene REL and avian reticuloendotheliosis viral oncogene homolog; REL.

Encoded by the REL gene, proto-oncogene c-Rel is a transcription factor that is a member of the Rel/NFKB family, which also includes RELA, RELB, NFKB1 and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (Belguise and Sonenshein, 2007) (PubMed 18037997).

Rabbit anti Human proto-oncogene c-Rel antibody detects a band of 69 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti proto-oncogene c-Rel detects a band of approximately 69 kDa in Jurkat cell lysates.
Product Form
Purified IgG - liquid
Preparation
Rabbit Ig fraction prepared by ammonium sulphate precipitation.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3).
Immunogen
Proto-oncogene c-Rel-His fusion protein
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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UniProt
Q04864
Entrez Gene
REL
GO Terms
GO:0005515 protein binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005634 nucleus
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade

VPA00227

151204

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